Vliv filosofického myšlení na rozvoj společnosti ve starověku a středověku

Abstract

The article`s goal is to compare impacts of philosophy on progress of society and economy with regard to influence of religion. Influence of philosophy is studied on historical development of society in antiquity and medieval age. It was the period of time, which was influenced by religion changes the most, which leaded to different development of society depending on free hand. This assumption is showed on development of ancient Greece, classic China, the Arab world and medieval catholic Europe. Those regions proceeded periods of economic prosperity and decline depending on ability of philosophy to resisted religion interventionism. In addition, on Europe history is pointed out the way how ancient knowledge was passing the history through particular regions which put emphasis on human development.

Genotoxicity Assessment of Drinking Water Disinfection Byproducts by DNA Damage and Repair Pathway Profiling Analysis

“…It was reported to induce cellular ROS, oxidative DNA adduct 8-OHdG, and activation of the Nrf2/ARE pathway (associated with oxidative stress) with an effect on intracellular antioxidant systems including GSH/GSSG and antioxidant enzymes. 20,21,43,64 Examination and comparison of DNA damage and repair pathway activation profiles among DBPs suggest that genotoxicity of DBPs may be structure-dependent. For example, dichloroacetonitrile, dibromoacetonitrile, and two haloaldehydes analyzed in this study induced a wide range of pathway activations likely reflecting their strong oxidative damage to DNA structure.…”

“…3,13 Genotoxicity mechanisms of DBPs are also strongly related to their structures. For example, for halogenated DBPs, oxidative stress-induced DNA damage [14][15][16][17][18][19][20][21] and DNA alkylation [22][23][24][25] are two major mechanisms. Halonitriles may also induce genomic damage by cell cycle disruption and the induction of hyperploidy.…”