Vitreoretinal Surgery in Uveitis: From Old to New Concepts - A Review

Mazzeo, Thiago José Muniz Machado; Freire, Raimunda Cristina Mendonça; Machado, Cleide Guimarães; Gomes, André Luís; Curi, André Luiz Land

doi:10.1080/09273948.2023.2193842

Cited by 2 publications

(3 citation statements)

References 149 publications

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“…The consensus among authors is that surgical intervention for ERM in uveitis is appropriate for eyes experiencing progressive structural and functional deterioration. However, due to potential outcome variability in certain cases (when compared to idiopathic ERM), such surgery should only be recommended once intraocular inflammation is effectively managed and conservative approaches have proven ineffective [ 77 ]. PPV has become increasingly utilized in uveitic cases for both diagnostic and therapeutic purposes [ 31 , 77 – 79 ].…”

Section: Surgical Managementmentioning

confidence: 99%

“…However, due to potential outcome variability in certain cases (when compared to idiopathic ERM), such surgery should only be recommended once intraocular inflammation is effectively managed and conservative approaches have proven ineffective [ 77 ]. PPV has become increasingly utilized in uveitic cases for both diagnostic and therapeutic purposes [ 31 , 77 – 79 ]. The introduction of microincision vitrectomy surgery (MIVS) has expanded the indications for PPV in uveitis due to its advantages over the conventional 20G vitrectomy, including shorter surgical duration, reduced patient discomfort, minimized conjunctival scarring, and decreased complications.…”

Section: Surgical Managementmentioning

confidence: 99%

“…While certain structural complications of uveitis may exhibit positive responses to surgery, the visual outcomes still entail some level of uncertainty. Conversely, diagnostic vitrectomy with appropriate ancillary testing remains an important method for evaluating and diagnosing uveitis in a considerable number of patients [ 77 ]. Table 1 provides a summary detailing the surgical outcomes in patients with uveitis undergoing intervention for epiretinal membranes.…”

Section: Surgical Managementmentioning

confidence: 99%

See 2 more Smart Citations

Epiretinal membranes in patients with uveitis: an update on the current state of management

Kalogeropoulos,

Lotery,

Gupta

et al. 2024

Int Ophthalmol

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Purpose This review aims to summarize the current knowledge concerning the clinical features, diagnostic work-up, and therapeutic approach of uveitic epiretinal membranes (ERM). Methods A thorough investigation of the literature was conducted using the PubMed database. Additionally, a complementary search was carried out on Google Scholar to ensure the inclusion of all relevant items in the collection. Results ERM is an abnormal layer at the vitreoretinal interface, resulting from myofibroblastic cell proliferation along the inner surface of the central retina, causing visual impairment. Known by various names, ERM has diverse causes, including idiopathic or secondary factors, with ophthalmic imaging techniques like OCT improving detection. In uveitis, ERM occurrence is common, and surgical intervention involves pars plana vitrectomy with ERM peeling, although debates persist on optimal approaches. Conclusions Histopathological studies and OCT advancements improved ERM understanding, revealing a diverse group of diseases without a unified model. Consensus supports surgery for uveitic ERM in progressive cases, but variability requires careful consideration and effective inflammation management. OCT biomarkers, deep learning, and surgical advances may enhance outcomes, and medical interventions and robotics show promise for early ERM intervention.

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Section: Surgical Managementmentioning

confidence: 99%