Vitis vinifera (Vine Grape) as a Valuable Cosmetic Raw Material

Sharafan, Marta; Malinowska, Magdalena; Ekiert, Halina; Kwaśniak, Beata; Sikora, Elżbieta; Szopa, Agnieszka

doi:10.3390/pharmaceutics15051372

Cited by 9 publications

(7 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Vitis vinifera is a climbing vine cultivated worldwide, and the largest fruit crop in the world [ 131 ]. It has served as a nutritional supplement or food colouring additive in the food industry [ 42 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Medicinal plants and natural products for treating overactive bladder

Chen,

Hoi,

Lee

2024

Chin Med

View full text Add to dashboard Cite

Background Overactive bladder (OAB) presents a high prevalence of 16–18% worldwide. The pathophysiology of OAB is still poorly understood while effective therapy or countermeasure are very limited. On the other hand, medicinal plants and herbal remedies have been utilized for treating lower urinary tract symptoms (LUTS) in both Eastern and Western cultures since ancient times. In recent years, accumulating progress has also been made in OAB treatment research by using medicinal plants. Methods Relevant literature on the studies of medicinal plants and herbs used to treat OAB was reviewed. The medicinal plants were summarized and categorized into two groups, single-herb medications and herbal formulations. Results The present review has summarized current understanding of OAB’s pathophysiology, its available treatments and new drug targets. Medicinal plants and natural products which have been used or have shown potential for OAB treatment were updated and comprehensively categorized. Studies on a wide variety of medicinal plants showed promising results, although only a few phytochemicals have been isolated and identified. Until now, none of these herbal compounds have been further developed into clinical therapeutics for OAB. Conclusions This review provides the basis for discovering and designing new phytopharmaceutical candidates with effective and well-tolerated properties to treat OAB. Increasing evidences indicate new strategies with alternative herbal treatment for OAB have high efficacy and safety, showing great promise for their clinical use. Future studies in a rigorously designed controlled manner will be beneficial to further support the eligibility of herbal treatment as OAB therapeutics.

show abstract

Section: Introductionmentioning

confidence: 99%

“…Furthermore, the safety of V. vinifera has been well-established, further enhancing its appeal for cosmetic applications. [ 131 ].…”

Section: Introductionmentioning

confidence: 99%

Medicinal plants and natural products for treating overactive bladder

Chen,

Hoi,

Lee

2024

Chin Med

View full text Add to dashboard Cite

show abstract

“…For example, grape seed extract is suggested as a humectant, coloring agent, and hair and skin conditioner [ 20 ]. Grape-based cosmetics have many anti-aging properties and do not irritate the skin [ 21 ]. Nowadays, many natural cosmetics companies are using raw materials from food sector waste, and they are putting more effort into developing cosmetics with a low negative impact on the environment.…”

Section: Introductionmentioning

confidence: 99%

Exhausted Grape Seed Residues as a Valuable Source of Antioxidant Molecules for the Formulation of Biocompatible Cosmetic Scrubs

Salem,

Rajha,

Sunoqrot

et al. 2023

Molecules

View full text Add to dashboard Cite

Grape seed of Obeidi, a white Lebanese autochthonous variety, was previously tested in different studies as a valuable source of bioactive molecules such as polyphenols, oils, and proteins by means of extraction procedures for the development of cosmetic and therapeutic products. However, an un-valorized, exhausted grape seed residue remains as “secondary waste” after the extraction processes. In this study, the exhausted seeds have been further exploited to produce cosmetic scrubs capable of releasing antioxidant molecules during the exfoliation process, in accordance with the principles of the circular economy and going toward a zero-waste process. The deep characterization of the exhausted seeds confirmed the presence of antioxidant phenolic molecules including gallic acid, catechins and protocatechuic acid (0.13, 0.126, and 0.089 mg/g of dry matter DM), and a high phenolic content (11.85 mg gallic acid equivalents (GAE)/g of dry matter (DM)). Moreover, these residues were shown to possess a sandy texture (Hausner ratio (HR): 1.154, Carr index (CI): 0.133, and angle of repose: 31.62 (°) degrees), similar to commercial natural exfoliants. In this respect, exhausted Obeidi grape seed residues were incorporated at increasing concentrations (0.5, 1, 1.5, and 2% w/w) in a cosmetic scrub, and stored for 5 weeks at 4, 25, and 50 °C for stability testing. All tested scrub formulations exhibited good spreadability with a spread diameter of 3.6–4.7 cm and excellent physical stability, as no phase separation or color change were observed after four cycles of heat shock at 4 and 50 °C. Finally, an in vivo skin irritation test showed that the scrub enriched with 1.5% of exhausted Obeidi grape seed residues was the most promising formulation, as it possessed a high amount of phenolic molecules (0.042 ± 0.001 mg GAE/mL of scrub) and good stability and could be safely applied to the skin with no irritation phenomena. Overall results underlined that exhausted grape seed residues can be transformed into promising systems for both physical and chemical exfoliation, thus confirming the importance of the effective exploitation of agro-industrial by-products for the development of high value cosmeceutics towards a more sustainable and zero-waste approach.

show abstract

“…Vitis vinifera L.-vine grape (Vitaceae) is a well-known species found in Europe (France, Italy, Spain), Asia (China) and the Americas (United States, Argentina, Chile) [1]. The raw materials obtained from the plant (fruit, seed, leaf, stem, cane, root) are widely used Molecules 2023, 28, 6868 2 of 19 in food, pharmaceutical, and cosmetic industries.…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, V. vinifera extracts exhibit antioxidant, antimicrobial, anti-inflammatory, and skin-whitening activities, which are important in cosmetology [10][11][12][13][14][15][16][17][18]. The biological activity of V. vinifera can be attributed to its rich phytochemical composition [1,19,20]. The grape varieties that were the subjects of this research belong to the so-called PIWI varieties, collected in Jura region (South Poland), that are resistant to pathogens and cold climate.…”

Section: Introductionmentioning

confidence: 99%

Shoot Cultures of Vitis vinifera (Vine Grape) Different Cultivars as a Promising Innovative Cosmetic Raw Material—Phytochemical Profiling, Antioxidant Potential, and Whitening Activity

Sharafan,

Malinowska,

Kubicz

et al. 2023

Molecules

Self Cite

View full text Add to dashboard Cite

The primary purpose of this work was the initiation and optimization of shoot cultures of different Vitis vinifera L. cultivars: cv. Chardonnay, cv. Hibernal, cv. Riesling, cv. Johanniter, cv. Solaris, cv. Cabernet Cortis, and cv. Regent. Cultures were maintained on 30-day growth cycles using two media, Murashige and Skoog (MS) and Schenk and Hildebrandt (SH), with various concentrations of plant growth regulators. Tested media (‘W1’–‘W4’) contained varying concentrations of 6-benzylaminopurine (BA) in addition to indole-3-butyric acid (IBA) and 1-naphthaleneacetic acid (NAA). High performance liquid chromatography coupled with mass spectrometry (UPLC–MS) was used for metabolomic profiling. In all tested extracts, 45 compounds were identified (6 amino acids, 4 phenolic acids, 13 flavan-3-ols, 3 flavonols, and 19 stilbenoids). Principal component analysis (PCA) was performed to assess the influence of the genotype and medium on metabolic content. PCA showed that metabolic content was mainly influenced by genotype and to a lesser extent by medium composition. MS media variants induced the amino acid, procyanidin, and flavan-3-ol production. In addition, the antioxidant potential and anti-tyrosinase activity was measured spectrophotometrically. The studies on antioxidant activity clearly reveal very high efficiency in reducing free radicals in the tested extracts. The strongest tyrosinase inhibition capacity was proved for shoots cv. Hibernal cultured in SH medium and supplemented with NAA, with an inhibition of 17.50%. These studies show that in vitro cultures of V. vinifera cvs. can be proposed as an alternative source of plant material that can be potentially used in cosmetic industry.

show abstract

Vitis vinifera (Vine Grape) as a Valuable Cosmetic Raw Material

Cited by 9 publications

References 56 publications

Medicinal plants and natural products for treating overactive bladder

Medicinal plants and natural products for treating overactive bladder

Exhausted Grape Seed Residues as a Valuable Source of Antioxidant Molecules for the Formulation of Biocompatible Cosmetic Scrubs

Shoot Cultures of Vitis vinifera (Vine Grape) Different Cultivars as a Promising Innovative Cosmetic Raw Material—Phytochemical Profiling, Antioxidant Potential, and Whitening Activity

Contact Info

Product

Resources

About