Vitiligo in the Nigerian African: a study of 351 patients in Benin City, Nigeria

Onunu, A N; Kubeyinje, E. P.

doi:10.1046/j.1365-4362.2003.01908.x

Cited by 60 publications

(62 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Em dois trabalhos realizados com pacientes de diferentes idades, o vitiligo focal foi a manifestação inicial na maioria dos casos, coincidindo com os dados encontrados neste trabalho. 13,14 Em relação à superfície corporal afetada, o acometimento era mínimo (inferior a 1%) em 71,8% dos casos, sendo que nenhum paciente apresentava acometimento superior a 50%. Estudo que faz referência à superfície corporal acometida também encontrou pequeno percentual, com 96,4% dos pacientes mostrando acometimento inferior a 20%.…”

Section: Discussionunclassified

Vitiligo na infância: características clínicas e epidemiológicas

Silva¹,

Pereira²,

Ribeiro³

2007

An. Bras. Dermatol.

View full text Add to dashboard Cite

show abstract

Section: Discussionunclassified

Vitiligo na infância: características clínicas e epidemiológicas

Silva¹,

Pereira²,

Ribeiro³

2007

An. Bras. Dermatol.

View full text Add to dashboard Cite

show abstract

“…Moreover, generalized vitiligo is a component of the APECED (APS type I) and Schmidt (APS type II) multiple autoimmune disease syndromes, and in small studies has been associated with AITD (39,40), pernicious anemia (41,42), Addison's disease (43), and perhaps alopecia areata (44,45). Much larger surveys of vitiligo patients (14,15,(46)(47)(48) have generally found elevated frequencies of AITD, pernicious anemia, rheumatoid arthritis, psoriasis, type 1 diabetes, Addison's disease, and systemic lupus erythematosus; about 15%-25% of patients with generalized vitiligo have at least one additional concomitant autoimmune disorder. Moreover, these same autoimmune diseases also occur with increased prevalence in vitiligo patients' first-degree relatives, regardless of whether or not those relatives have vitiligo themselves (14,15).…”

Section: Epidemiology Of Generalized Vitiligo and Associated Autoimmumentioning

confidence: 99%

Shared Genetic Relationships Underlying Generalized Vitiligo and Autoimmune Thyroid Disease

Spritz

2010

Thyroid

View full text Add to dashboard Cite

“…7 The site of onset and distribution of lesions differ according to age and region of the study population, but the most affected sites are, respectively, the head, limbs and trunk; the less affected sites are mucous membranes. 8,9 This pigmentation disorder follows a suggested classification because not all cases behave in the same way. The classification is based on the distribution and size of the depigmented area.…”

Section: Introductionmentioning

confidence: 99%

Perfil epidemiológico dos pacientes com vitiligo e sua associação com doenças da tireoide

Nunes

Esser

2011

An. Bras. Dermatol.

View full text Add to dashboard Cite

BACKGROUND: Vitiligo is considered the most frequent acquired hypomelanosis. Although its pathogenesis is uncertain, it is believed that autoimmune etiology is the most plausible. This theory is based on the coexistence of vitiligo with autoimmune diseases. Objectives: To describe the epidemiological profile of vitiligo patients and to estimate the prevalence of the association of vitiligo with autoimmune thyroid diseases. Methods: A cross-sectional study was conducted through analysis of the medical records of patients diagnosed with vitiligo in the AME-UNISUL Outpatient Clinic of Dermatology and at HU-UFSC. The clinical and laboratorial characteristics of these patients were assessed. Results: 85 medical records were evaluated; 56 patients were female, with a mean age of 37.14 years and mean onset age of 25.25 years. Vitiligo vulgaris occurred in 70.6%. Autoimmune thyroid diseases were found in 22.4%. Other autoimmune diseases were identified in 5.9%. Patients with positive thyroid autoantibodies showed a probability of extension of vitiligo greater than 25%. There was no statistical difference with regard to the clinical characteristics of vitiligo in patients with or without autoimmune thyroiditis with hormonal change. Conclusion: The findings of this study are similar to those obtained by other authors, showing that autoimmune thyroid diseases are more common in patients with vitiligo. Keywords: Autoimmunity; Thyroid diseases; Vitiligo Resumo: FUNDAMENTO: O vitiligo é considerado a hipomelanose adquirida mais frequente. Apesar de sua etiopatogenia ser incerta, acredita-se que a etiologia autoimune seja a mais plausível, teoria que se fundamenta na concomitância de vitiligo com doenças autoimunes. OBJETIVOS: Traçar o perfil epidemiológico dos pacientes com vitiligo e estimar a prevalência da associação de vitiligo com doenças autoimunes da tireoide. MÉTODOS: Efetuou-se um estudo transversal, analisando-se prontuários dos pacientes com diagnóstico de vitiligo atendidos no Ambulatório de Dermatologia AME-Unisul e do HU-UFSC. Avaliaram-se as características clínicas e laboratoriais desses pacientes. RESULTADOS: Foram avaliados 85 prontuários, sendo 56 do sexo feminino, com idade média de 37,14 anos e idade média de início de 25,25 anos. O vitiligo vulgar ocorreu em 70,6% dos casos. As doenças autoimunes da tireoide foram encontradas em 22,4% dos casos. Outras doenças autoimunes foram identificadas em 5,9% dos casos. Os pacientes com anticorpos antitireoidianos positivos revelaram uma probabilidade elevada de extensão do vitiligo maior que 25%. Não houve diferença estatística quanto às características clínicas do vitiligo em portadores ou não de tireoidite autoimune com alteração hormonal. CONCLUSÃO: Os resultados deste estudo são similares aos de outros autores, mostrando que as doenças autoimunes da tireoide são mais frequentes nos pacientes com vitiligo.

show abstract

Vitiligo in the Nigerian African: a study of 351 patients in Benin City, Nigeria

Abstract: Vitiligo on darkly pigmented skin is often a very striking disease. Our findings show that the pattern of vitiligo is similar to that reported from other parts of the world. The high level of social stigmatization is due to confusion with leprosy.

Cited by 60 publications

References 11 publications

Vitiligo na infância: características clínicas e epidemiológicas

Vitiligo na infância: características clínicas e epidemiológicas

Shared Genetic Relationships Underlying Generalized Vitiligo and Autoimmune Thyroid Disease

Perfil epidemiológico dos pacientes com vitiligo e sua associação com doenças da tireoide

Contact Info

Product

Resources

About