2015
DOI: 10.1111/bjd.13432
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Vitiligo Area Scoring Index and Vitiligo European Task Force assessment: reliable and responsive instruments to measure the degree of depigmentation in vitiligo

Abstract: VASI and VETFa are reliable and responsive instruments to assess the degree of depigmentation in vitiligo. VASI and VETFa for depigmentation are potential instruments for vitiligo research in the future. However, for use in individual patient care, caution is needed when interpreting score changes in individual patients because of the relatively large SDC.

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Cited by 65 publications
(70 citation statements)
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“…The VASI was calculated using a formula for summing all body areas (by hand unit) according to level of depigmentation . Disease activity was classified into three groups as progressive, regressive, or stable.…”
Section: Methodsmentioning
confidence: 99%
“…The VASI was calculated using a formula for summing all body areas (by hand unit) according to level of depigmentation . Disease activity was classified into three groups as progressive, regressive, or stable.…”
Section: Methodsmentioning
confidence: 99%
“…The VASI relies on an estimation of affected BSA, with limited sensitivity to change (>4.7% BSA). 5 Newer outcome measures may provide more sensitive options for monitoring responses. Simvastatin may induce myopathy at higher doses; however, topical treatment may allow the delivery of sufficiently high local concentrations without systemic toxicity and could be tested in larger studies.…”
Section: To the Editormentioning
confidence: 99%
“…A common misconception is that biomarkers of treatment response are unnecessary, since the skin can be observed clinically; however, even the earliest clinical changes in vitiligo take 2-3 months to become apparent due to the time required for melanocyte precursors to proliferate, migrate, differentiate, and produce pigment. Measurable responses require 6 months or more, and current outcome measures are largely subjective and insensitive to small changes 8,9 . Thus, relying only on observable changes in skin pigmentation is problematic.…”
Section: Introductionmentioning
confidence: 99%