Vitiligo

Stiegler, Julia; Brickley, Sylvana

doi:10.1097/jdn.0000000000000589

Cited by 1 publication

(1 citation statement)

References 54 publications

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“…Vitiligo-like depigmentation and melanoma are common skin conditions observed in gray horses as they age, with a prevalence of up to 80% in horses aged 15 years or older [102]. Vitiligo is caused by the loss of melanocytes in the skin, resulting in white patches among areas of hyperpigmentation [103]. On the other hand, melanomas typically appear as firm black nodules and tend to develop in regions such as the tail root, anus, genitals, and periocular areas.…”

Section: Vitiligo and Melanomamentioning

confidence: 99%

Coloration in Equine: Overview of Candidate Genes Associated with Coat Color Phenotypes

Liu,

Peng,

Zhang

et al. 2024

Animals

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Variation in coat color among equids has attracted significant interest in genetics and breeding research. The range of colors is primarily determined by the type, concentration, and distribution of melanin pigments, with the balance between eumelanin and pheomelanin influenced by numerous genetic factors. Advances in genomic and sequencing technologies have enabled the identification of several candidate genes that influence coat color, thereby clarifying the genetic basis of these diverse phenotypes. In this review, we concisely categorize coat coloration in horses and donkeys, focusing on the biosynthesis and types of melanin involved in pigmentation. Moreover, we highlight the regulatory roles of some key candidate genes, such as MC1R, TYR, MITF, ASIP, and KIT, in coat color variation. Moreover, the review explores how coat color relates to selective breeding and specific equine diseases, offering valuable insights for developing breeding strategies that enhance both the esthetic and health aspects of equine species.

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Section: Vitiligo and Melanomamentioning

confidence: 99%