Vitamine D2 ou vitamine D3 ?

Mistretta, Virginie; Delanaye, Pierre; Chapelle, Jean-Paul; Souberbielle, Jean‐Claude

doi:10.1016/j.revmed.2008.03.003

Cited by 18 publications

(11 citation statements)

References 17 publications

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“…Barnett et al (1982) estimated from growth curves that dietary vitamin D 3 is roughly 3.3 times more potent than dietary vitamin D 2 in rainbow trout. The same appears to be true for humans, although many products for human consumption are fortified with vitamin D 2 (Armas et al 2004; Houghton & Vieth 2006; Mistretta et al 2008). Fish is considered to be an important natural source of vitamin D 3 .…”

Section: Dietary Requirement Of Vitamin Dmentioning

confidence: 89%

The significance of vitamin D for fish: a review

Lock

Waagbø²,

Bonga

et al. 2010

Aquaculture Nutrition

129

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Fish store large quantities of vitamin D in their liver and fat tissues, including the fat associated with muscle, and this makes fish an important dietary source of vitamin D. Fish do not synthesize vitamin D and are fully dependent on dietary sources to meet their requirement. Under natural circumstances planktonic vitamin D accumulates in the aquatic food chain. In aquaculture, formulated diets are used and vitamin D intake can be manipulated. The minimum dietary requirement for vitamin D has been established in several fish species. The role of vitamin D in fish physiology is still enigmatic. Till the 1970s there was consensus that fish accumulate but not metabolize vitamin D. There is substantial evidence now, four decades later, that fish have a vitamin D endocrine system with similar functions as in mammals. We here summarize the major characteristics of the fish vitamin D endocrine system. The hydroxylation of vitamin D to more polar metabolites, their plasma levels and protein-bound transport in blood plasma will be discussed. The vitamin D receptor profile, receptor distribution and responses to vitamin D are reviewed for the key target tissues (gill, intestine, kidney and bone). We will address the classical slower actions through transcription factors as well as the faster G-protein coupled (membrane) receptor mediated effects. We then review the dietary requirement of vitamin D in aquaculture and address some lesser known functions of the vitamin D endocrine system. KEY WORDS

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Section: Dietary Requirement Of Vitamin Dmentioning

confidence: 89%

The significance of vitamin D for fish: a review

Lock

Waagbø²,

Bonga

et al. 2010

Aquaculture Nutrition

129

View full text Add to dashboard Cite

show abstract

“…Indeed, the dietary sources of vitamin D are scarce, the only really significant ones being marine fatty fish, although egg yolk and some mushrooms could be additional sources [2]. Thus, in humans, the major source of vitamin D comes from the exposure of the skin to sunlight.…”

Section: Introductionmentioning

confidence: 99%

A Randomised, Double-Blinded, Placebo-Controlled, Parallel Study of Vitamin D3 Supplementation with Different Schemes Based on Multiples of 25,000 IU Doses

Cavalier

Faché²,

Souberbielle

2013

International Journal of Endocrinology

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Vitamin D (VTD) treatment is recommended in patients presenting different causes of diseases. To treat these patients, physicians rely on the different available pharmaceutical forms present in their country. Unfortunately, even in a given country, there is no consensus on the best way to treat the patients. In Belgium, VTD is mostly prescribed as ampoules containing 25,000 IU of VTD. In this randomised controlled study, we evaluated whether four therapeutic schemes using multiples of 25,000 IU of VTD according to basal vitamin D concentration were able to increase or maintain the 25(OH)D serum level above 30 ng/mL. We randomized 175 subjects who received the drug (n = 140) or placebo (n = 35). Total duration of the study was 12 weeks. Doses ranged from 4167 to 1667 IU/day. Blood sampling was performed at baseline and each 4 visits. In the treated (placebo) subjects, mean 25(OH)D serum concentration was 18.7 (19.1) ng/mL at baseline and 31.5 (20.7) ng/mL at w-12. At the end of the study, 57.1% of the subjects treated with VTD presented 25(OH)D serum concentration ≥30 ng/mL, whereas 94.3% were ≥20 ng/mL. In conclusion, the doses administered were safe and increased or maintained the 25(OH)D concentration ≥20 ng/mL. However, concentrations ≥30 ng/mL were only achieved in 57.1% of the subjects.

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“…1 Patient-level outcomes of vitamin D therapy that are considered to be of critical or high importance include mortality, cardiovascular events, rates of hospital admission, parathyroidectomy, fracture, musculoskeletal pain and quality of life. 1 London et al 2 suggested an association between low 1,25-dihydroxyvitamin D (1,25[OH]D) levels and arteriosclerosis and endothelial dysfunction in patients on dialysis. Two studies, one of them conducted in the Department of Dialysis, University Medical Centre Maribor, Maribor, Slovenia, have examined the potential link between vitamin D deficiency and mortality in haemodialysis (HD) patients; both studies showed that decreased endogenous vitamin D levels were associated with higher allcause early mortality.…”

Section: Introductionmentioning

confidence: 99%