Vitamin Therapy in Dermatology

Maynard, Merlin T.-R.

doi:10.1001/archderm.1940.01490110028005

Cited by 5 publications

(2 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Older studies indicate that oral vitamin D has therapeutic value in acne [ 80 - 82 ], and emerging studies are showing that topical vitamin D analogues have comedolytic properties [ 83 ]. It is also of note that vitamin D has antioxidant properties, can increase SOD and GSH-Px activity [ 84 , 85 ], and low levels are associated with symptoms of depression and anxiety [ 86 , 87 ].…”

Section: Lipid Peroxidation Acne and Mental Healthmentioning

confidence: 99%

Clinical implications of lipid peroxidation in acne vulgaris: old wine in new bottles

Bowe

Logan²

2010

Lipids Health Dis

View full text Add to dashboard Cite

Acne vulgaris is a common dermatological disorder, one that is frequently associated with depression, anxiety and other psychological sequelae. In recent years there has been an increasing focus on the extent to which oxidative stress is involved in the pathophysiology of acne. Emerging studies have shown that patients with acne are under increased cutaneous and systemic oxidative stress. Indeed, there are indications that lipid peroxidation itself is a match that lights an inflammatory cascade in acne. The notion that lipid peroxidation is a 'starter gun' in acne is not a new one; here we review the nearly 50-year-old lipid peroxidation theory and provide a historical perspective to the contemporary investigations and clinical implications.In addition, we present a novel hypothesis in which lipid peroxidation may be priming an increased susceptibility to co-morbid depression and anxiety in those with acne. The emerging research on the systemic burden of oxidative stress in acne sheds further light on the brain-skin axis. The recent findings also suggest potential avenues of approach for the treatment of acne via specific nutrients, dietary modifications, oral and topical interventions.

show abstract

Section: Lipid Peroxidation Acne and Mental Healthmentioning

confidence: 99%

Clinical implications of lipid peroxidation in acne vulgaris: old wine in new bottles

Bowe

Logan²

2010

Lipids Health Dis

View full text Add to dashboard Cite

show abstract

“…Concerning dietary factors, studies have been conducted to show the role of zinc in treatment of drug-resistant cases of depression (14,15). Also these kinds of performances have done for vitamin D and its effects on acne vulgaris (16)(17)(18). Vitamin D, as an antioxidant agent, would have positive impression on the disease (19,20).…”

Section: Introductionmentioning

confidence: 99%