Vitamin K2 and its Impact on Tooth Epigenetics

Gordeladze, Jan O.; Landin, Maria A.; Johnsen, Håvard Jostein Haugen Gaute Floer; Osmundsen, Harald

doi:10.5772/66383

Cited by 3 publications

(1 citation statement)

References 69 publications

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“…Vitamin K2 works in concert with calcium and vitamin D and appears to have a significant antioxidant role. Therefore, vitamin K2 can help to considerably reduce tooth decay while also appearing to play a prospective saliva-buffering role in the exocrine parotid and other salivary glands [ 14 ].…”

Section: The Beneficial Role Of Vitamin K2 In Physiological Processesmentioning

confidence: 99%

The Impact of Vitamin K2 (Menaquionones) in Children’s Health and Diseases: A Review of the Literature

Kozioł-Kozakowska

Maresz²

2022

Children

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Vitamin K2 activates vitamin K-dependent proteins that support many biological functions, such as bone mineralization, the inhibition of vascular stiffness, the improvement of endothelial function, the maintenance of strong teeth, brain development, joint health, and optimal body weight. Due to the transformation of food habits in developed countries over the last five decades, vitamin K and, specifically, vitamin K2 intakes among parents and their offspring have decreased significantly, resulting in serious health implications. The therapeutics used in pediatric practice (antibiotics and glucocorticoids) are also to blame for this situation. Low vitamin K status is much more frequent in newborns, due to both endogenous and exogenous insufficiencies. Just after birth vitamin K stores are low, and since human milk is relatively poor in this nutrient, breast-fed infants are at particular risk of a bleeding disorder called vitamin K deficiency bleeding. A pilot study showed that better vitamin K status is associated with lower rate of low-energy fracture incidence. An ongoing clinical trial is intended to address whether vitamin K2 and D3 supplementation might positively impact the biological process of bone healing. Vitamin K2 as menaquinone-7 (MK-7) has a documented history of safe and effective use. The lack of adverse effects of MK-7 makes it the ideal choice for supplementation by pregnant and nursing women and children, both healthy and suffering from various malabsorptions and health disorders, such as dyslipidemia, diabetes, thalassemia major (TM), cystic fibrosis (CF), inflammatory bowel diseases (IBD), and chronic liver diseases. Additionally, worthy of consideration is the use of vitamin K2 in obesity-related health outcomes.

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Section: The Beneficial Role Of Vitamin K2 In Physiological Processesmentioning

confidence: 99%

The Impact of Vitamin K2 (Menaquionones) in Children’s Health and Diseases: A Review of the Literature

Kozioł-Kozakowska

Maresz²

2022

Children

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Significant influence for vitamin K on different metabolic diseases according to positive effect on levels of both vitamin D, and calcium

Elbossaty¹

2018

Arch Biotechnol Biomed

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Vitamin K was discovered as nutrient of blood clotting. There are two main types of vitamin K, vitamin K1, and vitamin K2. Although the structure of vitamin k is stable but also, there are differences between them. Vitamin k1 is mainly present in dark green leafy plant; while vitamin k2 present in animal and fermented plant. There are different sources of vitamin k. The normal human body is required about 200μg/day from vitamin k in both forms. Vitamin k1 can easily converted into vitamin k2.There is big difference between work of types of vitamin k, where each one responsible for special job. Vitamin k play important role in various metabolic process; vitamin k especially k2 play important role in protect the body from heart attack, in addition to reduce the development of osteoporosis and bone disease in combination with vitamin D and calcium. Vitamin k responsible for increase the secretion of male sex hormone and infertility. Vitamin k is consider one of the most important vitamin, it can save human from death as result of precipitation of calcium on arteries. Due to the importance of vitamin k, this article will discuss vitamin k, its presence, and role in different diseases.

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Changes in Diet and Anthropometric Parameters in Children and Adolescents with Celiac Disease—One Year of Follow-Up

et al. 2021

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Celiac disease (CD) may cause numerous nutrient deficiencies that a proper gluten-free diet (GFD) should compensate for. The study group consists of 40 children, aged 8.43 years (SD 3.5), on average, in whom CD was diagnosed on the basis of clinical symptoms, immunological and histopathological results. The patients’ height, weight, diet and biochemical tests were assessed three times: before diagnosis, after six months, and following one year of GFD. After one year, the patients’ weight and height increased but nutritional status (body mass index, BMI percentile) did not change significantly. The children’s diet before diagnosis was similar to that of the general Polish population: insufficient implementation of the dietary norm for energy, fiber, calcium, iodine, iron as well as folic acid, vitamins D, K, and E was observed. Over the year, the GFD of the children with CD did not change significantly for most of the above nutrients, or the changes were not significant for the overall assessment of the diet. Celiac patients following GFD may have a higher risk of iron, calcium and folate deficiencies. These results confirm the need for personalized nutritional education aimed at excluding gluten from the diet, as well as balancing the diet properly, in patients with CD.

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Vitamin K2 and its Impact on Tooth Epigenetics

Cited by 3 publications

References 69 publications

The Impact of Vitamin K2 (Menaquionones) in Children’s Health and Diseases: A Review of the Literature

The Impact of Vitamin K2 (Menaquionones) in Children’s Health and Diseases: A Review of the Literature

Significant influence for vitamin K on different metabolic diseases according to positive effect on levels of both vitamin D, and calcium

Changes in Diet and Anthropometric Parameters in Children and Adolescents with Celiac Disease—One Year of Follow-Up

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