Vitamin E in Viral Inactivated Vaccines

Franchini, A.; Bertuzzi, Sara; Tosarelli, C.; Manfreda, Gerardo

doi:10.3382/ps.0740666

Cited by 35 publications

(15 citation statements)

References 8 publications

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“…Sahin et al (2001) reported that 250 mg/kg α-tocopherol acetate decreased serum AST and ALT in broilers reared under heat stress (32 °C). Franchini et al (1995) also noted that the AST level increased with vitamin E supplementation in young turkey; however, it decreased in old turkey (140 days old) which is quite consistent to our study. In this study, the reduction of serum AST and ALT seemed to be due to the antioxidant effect of vitamin E supplementation.…”

Section: Discussionsupporting

confidence: 92%

Supplementation of vitamins, probiotics and proteins on oxidative stress, enzymes and hormones in post-moult male broiler breeders

et al. 2013

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This study was planned to investigate the comparative effect of vitamin E and C, probiotics, protein level and the combination of these treatments on body weight, serum total antioxidant capacity (TAC), total oxidant status (TOS), oxidative stress index (OSI), aspartate aminotransferase (AST), alanine aminotransferase (ALT), triiodothyronine (T 3 ), thyroxine (T 4 ), cortisol and some minerals in Zn-induced male broiler breeders. A total of 180 Hubbard male broiler breeders (65 weeks of age) were induced to moult. After moulting, the birds were randomly distributed into six groups. One group was fed vitamin E (100 IU/kg feed), second group was fed vitamin C (500 IU/kg feed), third group was fed probiotics (50 mg/L), fourth group was fed lower protein level (14 % crude protein) and the fifth group was fed the combination of the mentioned treatments. The sixth group served as control. The results revealed that serum TAC significantly increased (P<0.05) while TOS and OSI decreased (P<0.05) in the vitamin E fed group compared to the other treated groups. The analyses of the samples indicated that AST and ALT decreased significantly in the vitamin E supplemented group while T 3 and T 4 increased significantly as a result of this treatment. Cortisol concentration decreased significantly in the vitamin E fed group. Serum Mg increased significantly in the vitamin E supplemented group. The results indicated that the physiological biochemistry disrupted in male breeders as a consequence of moulting could be compensated by feeding vitamin E.

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Section: Discussionsupporting

confidence: 92%

Supplementation of vitamins, probiotics and proteins on oxidative stress, enzymes and hormones in post-moult male broiler breeders

et al. 2013

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“…This contact with the high local concentration of vitamin E (e.g. approximately 116 mg α-tocopherol per dose used) [23,24], at the site of action assures the most favourable immunoenhancing effect of the vitamin, far more effectively than is possible by its dietary administration [25].…”

Section: Immunoadjuvantmentioning

confidence: 99%

“…Also vitamin E has been successfully tested as an adjuvant in chicks showing, a significant improvement in antibody titers to Newcastle disease virus and E. coli antigens in the groups receiving the injection [23,24]. No data are available for pigs.…”

Section: Immunoadjuvantmentioning

confidence: 99%

Vitamin E in immunity and reproductive performance in pigs

Pinelli‐Saavedra

2003

Reprod. Nutr. Dev.

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-This review is focused on studies of vitamin E in immunity and reproductive performance in pigs. There are reports that vitamin E can have a positive effect on some parameters of the immune system in pigs. The optimal level of vitamin E needed to improve the immune system has not been determined because of several factors such as the composition of the diet, feed consumption, the rate of animal growth and living conditions or stress. Moreover, the way of action of vitamin E in enhancing immunity is still unclear but according to reports it may have antioxidant properties as well as an immunomodulator effect. In several studies, an increase in litter size and a reduction of preweaning piglet mortality have resulted from increasing dietary vitamin E intake during gestation or by intramuscular injection of vitamin E and/or selenium. However, according to reports, the positive effect of vitamin E on reproductive performance remains unclear due to the low number of animals used in most experiments.vitamin E / pig / immunity / reproductive performance / placental transfer

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“…Apart from its protective effect on lipid peroxidation, the immunoregulatory effects of dietary vitamin E on humoral and cell-mediated immunity are well known (Franchini et al, 1995;Raza et al, 1997;Shadaksharappa et al, 1997;Gu et al, 1999). Vitamin E improves the action of phagocytic cells, the responsiveness of antibodies to mitogens, and passive immune transfer (Tizzard, 1987).…”

Section: Introductionmentioning

confidence: 96%

A Protective Effect of Vitamin E and Selenium in Ameliorating the Immunotoxicity of Malathion in Chicks

2006

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A study was conducted to determine whether a combination of vitamin E and selenium was able to counteract the immunosuppressive effects of chronic toxicity of malathion in chicks. The chicks were divided into three groups. The first group received malathion 10 mg/kg body weight; the second group received the same dose of malathion but was supplemented with vitamin E and selenium for 60 days; and the third group served as the control. The concentration of total immunoglobulins and circulatory immune complexes decreased following the administration of malathion, whereas the supplementation of the diet with vitamin E and selenium partially counteracted this effect. The histopathological changes in the bursa of Fabricius due to malathion were consistent with these findings. Supplementation with vitamin E and selenium partially ameliorated the degenerative changes in the bursa of Fabricius.

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Vitamin E in Viral Inactivated Vaccines

Cited by 35 publications

References 8 publications

Supplementation of vitamins, probiotics and proteins on oxidative stress, enzymes and hormones in post-moult male broiler breeders

Supplementation of vitamins, probiotics and proteins on oxidative stress, enzymes and hormones in post-moult male broiler breeders

Vitamin E in immunity and reproductive performance in pigs

A Protective Effect of Vitamin E and Selenium in Ameliorating the Immunotoxicity of Malathion in Chicks

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