2010
DOI: 10.1111/j.1532-5415.2010.02949.x
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Vitamin D Treatment for the Prevention of Falls in Older Adults: Systematic Review and Meta‐Analysis

Abstract: Objectives To systematically review and quantitatively synthesize the effect of vitamin D therapy on fall prevention in older adults. Design Systematic review and meta-analysis. Setting MEDLINE, CINAHL,Web of Science, EMBASE, Cochrane Library, LILACS, bibliographies of selected articles, and previous systematic reviews through February 2009 were searched for eligible studies. Participants Older adults (aged ≥60 years) who participated in randomized controlled trials that investigated the effectiveness of… Show more

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Cited by 204 publications
(136 citation statements)
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References 50 publications
(261 reference statements)
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“…Eight meta-analyses [17][18][19][20][21][22][23][24] of vitamin D levels and falls have been conducted, some with conflicting results. Online Table A provides an overview of these meta-analyses, including populations, outcomes and other methodological issues.…”
Section: Systematic Review/meta-analysismentioning
confidence: 99%
“…Eight meta-analyses [17][18][19][20][21][22][23][24] of vitamin D levels and falls have been conducted, some with conflicting results. Online Table A provides an overview of these meta-analyses, including populations, outcomes and other methodological issues.…”
Section: Systematic Review/meta-analysismentioning
confidence: 99%
“…A serum concentration of 25 OH vitamin D of at least 20 ng/mL is required to maintain parathyroid hormone (PTH) within the normal range and this hormone is required for bone and muscle functioning and to prevent osteomalacia (13). Vitamin D insufficiency can result in secondary hyperparathyroidism, increased bone resorption and increased low-energy trauma fracture (14). In secondary hyperparathyroidism, serum calcium levels are maintained by the resorption of calcium from bone and increased phosphorus loss in the kidneys (15).…”
Section: Introductionmentioning
confidence: 99%
“…D vitamini kalsiyum homeostazında kritik öneme sahiptir. D vitamininin düşme riskini ve kırık oluşumunu azalttığı, postmenopozal osteoporozu önlediği ve osteoporoz tedavisinde yer alması gerektiği çeşitli çalışmalarda gösterilmiştir (5,6). Birçok çalışmada D vitamini eksikliğinin kardiyovasküler risk faktörlerini, kanser sıklığını, multipl skleroz, metabolik, enfeksiyöz ve otoimmün hastalıkları arttırdığı belirtilmektedir (7,8).…”
Section: Introductionunclassified