Vitamin D supplementation associated with 12-weeks multimodal training in older women with low bone mineral density: A randomized double-blind placebo-controlled trial

Brech, Guilherme Carlos; Machado-Lima, Adriana; Bastos, Marta Ferreira; Bonifácio, Wilson De Jesus; Peterson, Mark D.; Takayama, Liliam; Pereira, Rosa Maria Rodrigues; Greve, Julia Maria D’Andréa; Alonso, Angélica Castilho

doi:10.1016/j.exger.2020.111211

Cited by 2 publications

(2 citation statements)

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“…To further build the evidence base on this matter, two recent studies have evaluated the potential effect of vitamin D supplementation on top of resistance exercise training. Brech et al [19] used a 12-week supervised, combined resistance and postural balance training program with or without vitamin D supplementation in 46 older women with low bone mineral density and vitamin D insufficiency (i.e. <30 ng/ml).…”

Section: Exercise Training and Vitamin D Supplementationmentioning

confidence: 99%

“…Although some minor benefits were observed for certain balance control measures, the vast majority of strength, functional, and balance outcomes was improved by the exercise program, with no additive effect of vitamin D supplementation. This lead the authors to conclude that vitamin D did not further improve muscle strength and postural balance in response to the combined exercise program [19]. Using a slightly different approach, Mølmen et al [20 ▪ ] attempted to prime the myocellular milieu for adaptations by first deploying a 12-week placebo-controlled vitamin D supplementation protocol, which was then followed by 13 weeks of continued supplementation combined with 2×/week, supervised whole-body resistance exercise training.…”

Section: Exercise Training and Vitamin D Supplementationmentioning

confidence: 99%

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Nutritional supplementation to enhance the efficacy of exercise training in older adults: what is the evidence from the latest randomized controlled trials?

Verdijk¹

2021

Current Opinion in Clinical Nutrition &Amp; Metabolic Care

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Purpose of review This review summarizes recent studies that assessed whether nutritional supplementation enhances the efficacy of exercise training in older adults, focusing on the benefits for physical/functional performance of protein, vitamin D, or multi-ingredient supplementation. Recent findings Studies applying long-term exercise training strongly support the benefits of different exercise regimens for muscle strength and function but most studies do not provide direct evidence for protein, vitamin D, or multi-ingredient supplementation to further augment such improvements in older adults. Several methodological limitations are addressed that likely limited the reliability to convincingly establish or refute any additive effects of supplementation. Only when specifically tailored to the population under study, ensuring proper intensity, duration, and adherence to exercise, and aiming for a daily intake of ∼1.5 g protein per kg body mass, and ∼800 IU of vitamin D supplementation, there appears to be some potential to augment the efficacy of long-term exercise training in older adults, with potentially greater benefits in compromised older subpopulations. Summary There is some support for the efficacy of nutritional supplementation to further augment the beneficial effects of prolonged exercise training in older adults but any intervention needs tailoring of both the exercise and the nutritional intervention towards the intended (sub)population.

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Section: Exercise Training and Vitamin D Supplementationmentioning

confidence: 99%

Section: Exercise Training and Vitamin D Supplementationmentioning

confidence: 99%

Nutritional supplementation to enhance the efficacy of exercise training in older adults: what is the evidence from the latest randomized controlled trials?

Verdijk¹

2021

Current Opinion in Clinical Nutrition &Amp; Metabolic Care

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Vitamin D, Falls and Balance Capacity Impacts in Older Adults: Update

Marks

2021

JARH

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Background Falls injuries continue to contribute to numerous premature deaths as well as high disability levels, and excess morbidity rates among older adults, worldwide. But can vitamin D account for excess falls injuries among older adults? This review specifically focuses on what is known about vitamin D in the context of postural stability or balance control, both fairly consistent independent predictors of falls among older adults. Methods and Procedures Drawn largely from a review of current relevant English language peer reviewed research publications published over the last 10 years detailing the relationship between vitamin D levels and balance control among the elderly, as this relates to falls injuries, evidence for any emerging consensus on this controversial topic was sought. Used to conduct the search were various key word combinations including: falls injuries and older adults, vitamin D or vitamin D deficiency and balance or postural control. The database used predominantly to provide input into this largely descriptive assessment and narrative overview was PUBMED. Results The prevailing data show falls injuries currently constitute a widespread costly major impediment to successful aging and longevity for many older adults, despite numerous efforts to prevent this disabling set of events over the past two to three decades. However, no consistent association appears to exist between the variables of vitamin D, falls, and balance attributes in the older population-despite years of research, regardless of study approach, and a strong rationale for hypothesizing a clinically meaningful relationship. Conclusion It is not possible to arrive at any universal recommendation concerning the value of vitamin D supplementation as regards its possible influence on balance capacity among older adults in the realm of falls prevention efforts, as has been frequently proposed. However, until more definitive research is conducted, there still appears sufficient justification for considering the screening of vulnerable aging adults for serum vitamin D levels, along with balance impairments, and intervening as required in the case of deficits in either or both of these possible falls determinants.

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Vitamin D supplementation associated with 12-weeks multimodal training in older women with low bone mineral density: A randomized double-blind placebo-controlled trial

Cited by 2 publications

References 37 publications

Nutritional supplementation to enhance the efficacy of exercise training in older adults: what is the evidence from the latest randomized controlled trials?

Nutritional supplementation to enhance the efficacy of exercise training in older adults: what is the evidence from the latest randomized controlled trials?

Vitamin D, Falls and Balance Capacity Impacts in Older Adults: Update

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