Vitamin D Status in Children in Greece and Its Relationship with Sunscreen Application

Feketea, Gavriela; Bocşan, Ioana Corina; Tsiros, Georgios; Voila, Panagiota; Stanciu, Luminita A.; Zdrenghea, Dumitru

doi:10.3390/children8020111

Cited by 8 publications

(6 citation statements)

References 37 publications

(44 reference statements)

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“…The incidence of atopic manifestations is typically higher among boys [7], and our results are in accordance with this gender difference. As in other studies [30], our study showed an inverse relationship between 25(OH)D level and age in healthy children and adolescents.…”

Section: Discussionsupporting

confidence: 91%

Vitamin D Levels in Asymptomatic Children and Adolescents with Atopy during the COVID-19 Era

Feketea

Vlacha

Tsiros³

et al. 2021

JPM

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This study assessed vitamin D status in asymptomatic children and adolescents in Greece, with and without atopy, and possible changes during the coronavirus disease 2019 (COVID-19) pandemic. Serum levels of 25-hydroxy-vitamin D (25(OH)D) and total immunoglobulin E (IgE), and eosinophil count were measured in 340 asymptomatic children and adolescents (155 males, 185 females), mean age 8.6 ± 4.6 years, recruited over a period of 24 months (February 2019–January 2021). Atopy, defined by high level of IgE for age, was associated with vitamin D deficient status (p = 0.041). Subjects with and without atopy showed similar rates of insufficient and normal levels of 25(OH)D. The median level of 25(OH)D was significantly higher in subjects recruited during the pandemic, when home confinement rules were observed, than before the pandemic, and significantly more children had normal levels of 25(OH)D (p < 0.001), but no differences were noticed for IgE levels or eosinophil count. These results support a link between vitamin D and allergic and infectious inflammations, and specifically the association of vitamin D deficiency with asymptomatic atopy, defined as increased IgE level for age.

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Section: Discussionsupporting

confidence: 91%

Vitamin D Levels in Asymptomatic Children and Adolescents with Atopy during the COVID-19 Era

Feketea

Vlacha

Tsiros³

et al. 2021

JPM

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“…9,17 These data also showed that VD status in early childhood was not affected by gender and was similar to that of Greek counterparts. 37 Vitamin D status in late-stage children and adolescents was influenced by gender, which differed from the findings of European and Greek counterparts. 9,37 These differences in VD status are thought to be related to supplemental VD intake and lifestyle (outdoor activities).…”

Section: The Status Of Vd Deficiency Insufficiency Adequacy or Excess...mentioning

confidence: 73%

Vitamin D status among residents of Molidawa Daur Autonomous Banner, Inner Mongolia, North China

Liang

Wen

et al. 2023

SMJ

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‫شمال‬ ‫في‬ ‫للمقيمني‬ )VD( ‫د‬ ‫فيتامني‬ ‫حلالة‬ ‫رجعي‬ ‫بأثر‬ ‫التحليل‬ ‫ألهداف:‬ ‫الشهرية.‬ ‫الشمس‬ ‫سطوع‬ ‫ساعات‬ ‫مبتوسط‬ ‫وعالقته‬ ‫منغوليا‬ ‫شرق‬ ‫د‬ ‫فيتامني‬ ‫هيدروكسي‬ ‫مصل‬ ‫عينات‬ ‫على‬ ‫الدراسة‬ ‫اشتملت‬ ‫املنهجية:‬ ‫في‬ ‫ا)‬ ً ‫ذكر‬ 2092( ‫ا‬ ً ‫خارجي‬ ‫ا‬ ‫مريضً‬ 4982 ‫من‬ ]s-25)OH(D[ ‫من‬ ‫الفترة‬ ‫خالل‬ ‫الصني‬ ‫هولونبوير،‬ ‫الشعبي،‬ ‫املستقل‬ ‫داور‬ ‫داوا‬ ‫مولي‬ ‫مستشفى‬ ‫الدراسة.‬ ‫هذه‬ ‫في‬ ‫2202م‬ ‫يناير‬ ‫إلى‬ ‫8102م‬ ‫يوليو‬ ‫نانومول/‬ 53.3 ‫حوالي‬ s-25)OH(D ‫الكلي‬ ‫الوسيط‬ ‫كان‬ ‫النتائج:‬ 30-50( ‫ونقص‬ ، ‫نانومول/لتر)‬ 30 ‫من‬ ‫(أقل‬ VD ‫فيتامني‬ ‫عجز‬ ‫لتر،‬ ‫من‬ ‫(أكثر‬ ‫وفائض‬ ‫نانومول/لتر)‬ 50-250>( ‫وكافي‬ ‫/لتر)،‬ ‫نانومول‬ 30% ،)796/4982(16% ‫التاليه‬ ‫النسب‬ ‫وشكلوا‬ ‫نانومول/لتر)‬ 250 .)33/4982( ‫و%7.0‬ )2658/4982( 53.4% ،)1495/4982( ‫بني‬ s-25)OH(D ‫الوسيط‬ ‫في‬ ‫إحصائية‬ ‫داللة‬ ‫ذات‬ ‫فروق‬ ‫هناك‬ ‫كانت‬ ‫فيتامني‬ ‫انخفاض‬ ‫حالة‬ ‫كانت‬ .)p>0.001( ‫واجلنس‬ ‫العمرية‬ ‫والفئات‬ ‫الشهر‬ ‫والذكور‬ 54.6% ‫اإلناث‬ ‫في‬ ‫والعجز)‬ VD ‫نقص‬ ‫ذلك‬ ‫في‬ ‫مبا‬ ،LVDS ‫د‬ ‫العمرية‬ ‫الفئة‬ ‫حسب‬ ‫كبير‬ ‫بشكل‬ LVDS ‫تركيبة‬ ‫وتختلف‬ ،33.9% s-25)OH(D ‫متوسط‬ ‫ملستوى‬ ‫املتغير‬ ‫االجتاه‬ ‫كان‬ .)p>0.05( ‫والشهر‬ ‫طفيف.‬ ‫تغير‬ ‫مع‬ ‫الشهرية،‬ ‫الشمس‬ ‫سطوع‬ ‫ساعات‬ ‫ملتوسط‬ ‫ا‬ ً ‫مشابه‬ LVDS ‫يتأثر‬ .LVDS ‫في‬ ‫يعيشون‬ ‫السكان‬ ‫نصف‬ ‫حوالي‬ ‫اخلالصة:‬ ‫والعمر.‬ ‫واجلنس‬ ‫بالشهر‬ Objectives: To retrospectively analyze the vitamin D (VD) status of residents in northeastern Inner Mongolia and its relationship with the average monthly sunshine hours. Methods: Serum 25-hydroxyvitamin D[s-25(OH)D] samples from 4982 outpatients (2092 males) in Moli

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“…[2][3][4][7][8][9] There are not any significant differences presented between countries with greater exposure to the sun. 10 In general, a concentration of 25(OH)D > 20 ng/mL is a vitamin D sufficiency. An optimal concentration for children with ALL has not been defined in the literature.…”

Section: Discussionmentioning

confidence: 99%

The Vitamin D Status in Children With Newly Diagnosed Acute Lymphoblastic Leukemia and Its Potential Impact on the Primary Symptoms of Leukemia and Course of Induction Treatment

Małecka

Hennig

Jaworski

et al. 2022

Journal of Pediatric Hematology/Oncology

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Background: Vitamin D deficiency is ubiquitous within the population of children. A similar problem is recognized among pediatric patients with acute lymphoblastic leukemia. The purpose of this study was to analyze the prevalence of vitamin D deficiency and to investigate the connection between vitamin D status and the course of induction treatment of ALL. Materials and Methods: A cross-sectional study including 59 patients with newly diagnosed ALL from May 2017 until November 2020. Results: Vitamin D deficiency was found in 39% of the patients. There were no seasonal differences in vitamin D status. Patients with optimal 25(OH)D concentration presented more profound thrombocytopenia (P=0.015) and required more frequent platelet transfusions (P=0.018). Good prognosis factors such as B phenotype and hyperdiploidy were also more frequent among children with higher 25(OH)D concentration (P=0.01 and 0.014, respectively). Conclusions: The study showed that patients with a higher serum concentration of 25(OH)D presented deeper thrombocytopenia and needed more frequent transfusions. Moreover, those patients showed higher rates of B-cell leukemia and hyperdiploid karyotype. We did not find any influence of the possible exposure to sunlight (defined as the season of the year on admission) on serum 25(OH)D concentration, which supports the argument for supplementing vitamin D all year round. Moreover, the supplementing of vitamin D seems to be safe and does not cause any renal complications connected to calcium and phosphorus imbalance as no correlation between their levels and 25(OH)D concentration was found.

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Vitamin D Status in Children in Greece and Its Relationship with Sunscreen Application

Cited by 8 publications

References 37 publications

Vitamin D Levels in Asymptomatic Children and Adolescents with Atopy during the COVID-19 Era

Vitamin D Levels in Asymptomatic Children and Adolescents with Atopy during the COVID-19 Era

Vitamin D status among residents of Molidawa Daur Autonomous Banner, Inner Mongolia, North China

The Vitamin D Status in Children With Newly Diagnosed Acute Lymphoblastic Leukemia and Its Potential Impact on the Primary Symptoms of Leukemia and Course of Induction Treatment

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