Vitamin D status in anorexia nervosa: A meta‐analysis

Abstract

Although AN patients reported similar dietary VitD intake compared to HCs, AN patients had significantly lower 25OH-D and 1,25OH-D levels without supplementation. Conversely, supplementation with cholecalciferol fully normalized VitD serum levels. Future studies are needed to clarify the role of VitD supplementation in AN for improving bone health.

Osteoporosis in Frail Patients: A Consensus Paper of the Belgian Bone Club

“…However, in adolescents with AN, there is a low bone turnover state with a decrease in the levels of bone formation and resorption, as opposed to an increased bone turnover during normal adolescence [3]. Veronese et al conducted a meta-analysis of vitamin D status in AN patients [4]. They identified 15 studies (totalizing 927 participants; AN = 408 and healthy controls = 519) and observed that, although AN patients reported similar dietary vitamin D intake compared to healthy controls, AN patients had significantly lower levels of 25OHD and 1,25(OH) 2 D when not using vitamin D supplementation.…”

“…They identified 15 studies (totalizing 927 participants; AN = 408 and healthy controls = 519) and observed that, although AN patients reported similar dietary vitamin D intake compared to healthy controls, AN patients had significantly lower levels of 25OHD and 1,25(OH) 2 D when not using vitamin D supplementation. Conversely, supplementation with cholecalciferol fully normalized serum levels of vitamin D [4]. …”

Strong relationship between vitamin D status and bone mineral density in anorexia nervosa

“…Recently, Veronese et al [11] reported the results of a meta-analysis involving 15 studies with a total of 927 participants. They found that patients with AN have significantly lower serum levels of 25OHD and 1,25(OH)2D compared to healthy controls, while vitamin D introduced with diet was reported to be similar.…”

“…Kiriike et al [9] found that most of 29 patients with AN had normal vitamin D concentrations but normality was defined as 25 OHD N 16 ng/ml. Haagensen et al [10] showed a very low prevalence of vitamin D deficiency (b 20 ng/ml) in the AN group (2% vs. 24% among healthy controls), but the patients affected by AN had been encouraged to consume 400 IU vitamin D supplements daily by their primary eating disorder provider.Recently, Veronese et al [11] reported the results of a meta-analysis involving 15 studies with a total of 927 participants. They found that patients with AN have significantly lower serum levels of 25OHD and 1,25(OH)2D compared to healthy controls, while vitamin D introduced with diet was reported to be similar.…”

Vitamine bei Depression, Demenz & Co?

“…Typische Mangelzustände können dabei sowohl bei Abhängigkeitserkrankungen (am besten untersucht: Alkoholabhängigkeit) als auch bei Essstörungen wie Bulimie und Anorexie au reten. Bei den Essstörungen scheint sich besonders ein Vitamin-D-Mangel klinisch bedeutsam herauszustellen und das Risiko für eine Osteoporose zusätzlich substanziell zu erhöhen [1]. Andererseits gibt es viele weitere psychiatrische Erkrankungen wie psychotische Störungen und Depressionen, die durch bestimmte Medikamentenzufuhr behandelt werden könnten (Folat, allerdings meist zusammen mit anderen Vitaminen, B 6 , B 12 ).…”