Vitamin D status and viral response to therapy in hepatitis C infected children

Abstract

Adding vitamin D to conventional Peg/RBV therapy significantly improved the virological response and helped to prevent the risk of emerging bone fragility.

Levels of Interleukin-17 and Vitamin D and Their Correlation in Viral Hepatitis Patients

“…Similar to this result, the reported mean of vitamin D by [19] of HBV patients were lower than the reported mean of vitamin D by [20] of HCV patients, both in Egypt.…”

Camel Milk with Pegylated Interferon Alfa-2a and Ribavirin for Treatment-Naive Chronic Hepatitis C Genotype 2/ 3: An Open-Label, Randomized Controlled Trial

“…The results presented here indicate that 24 weeks of 250 cc of CM twice a day with Peg IFN/RBV achieved EVR12, ETR 24 , and SVR 24 of 60%, 90%, and 100%. Peg IFN/RBV achieved EVR 12 , ETR 24 , and SVR 24 of 15%, 70%, and 71%.…”

“…Results of a study conducted on 31 patients to investigate the role of vitamin D, suggested that the intake of 2000 units of vitamin per day, significantly decreased AST enzyme and viral load. According to this study, deficiency of vitamin D ef- fects the response to treatment; therefore, vitamin D supplementation could contribute to better responses (24). Vitamin content of camel milk could play a role in response improvement.…”

“…Peg IFN/RBV achieved EVR 12 , ETR 24 , and SVR 24 of 15%, 70%, and 71%. Higher levels of ETR 24 and SVR 24 could be attributed to differences in immunity status between various populations. All of the patients were white Iranians, therefore, race had no impact on the results of the current study.…”

“…The sample size was estimated as 45 considering probable patient loss (α type error of 0.05 and β error of 0.20 on the assumption of 65% SVR 24 in group A and of 90% SVR 24 in group B) and formula…”