2013
DOI: 10.1155/2013/471695
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Vitamin D Status and Spine Surgery Outcomes

Abstract: There is a high prevalence of hypovitaminosis D in patients with back pain regardless of whether or not they require surgical intervention. Furthermore, the risk of hypovitaminosis D is not limited to individuals with traditional clinical risk factors. Vitamin D plays an essential role in bone formation, maintenance, and remodeling, as well as muscle function. Published data indicate that hypovitaminosis D could adversely affect bone formation and muscle function in multiple ways. The literature contains numer… Show more

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Cited by 22 publications
(23 citation statements)
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“…10 In vitamin D status determination, only the metabolite 25(OH)D, as the major circulating form of vitamin D, is hugely recommended. 11 Recent data reported the potency (and the safety) of a single, large, oral 300,000 IU dose of cholecalciferol, in enhancing serum 25(OH)D concentration with concomitant decrease in parathyroid hormone secretion. 12 Purpose of this study was to investigate the effects of vitamin D serum concentration on lower third molar surgery, usually followed by swelling, pain and limited masticatory function.…”
mentioning
confidence: 99%
“…10 In vitamin D status determination, only the metabolite 25(OH)D, as the major circulating form of vitamin D, is hugely recommended. 11 Recent data reported the potency (and the safety) of a single, large, oral 300,000 IU dose of cholecalciferol, in enhancing serum 25(OH)D concentration with concomitant decrease in parathyroid hormone secretion. 12 Purpose of this study was to investigate the effects of vitamin D serum concentration on lower third molar surgery, usually followed by swelling, pain and limited masticatory function.…”
mentioning
confidence: 99%
“…Females are regarded to be at risk for vitamin D deficiency and many studies have confirmed this [19]. However, in a number of studies, there were no differences between female and male subjects for vitamin D deficiency [20] and even in some cases, it was shown a lower risk for hypovitaminosis D existed in females [1821].…”
Section: Discussionmentioning
confidence: 99%
“…Поліморфізм генів -рецепторів вітаміну D та їх зв'язок з розвитком остеоартрозу Для розкриття механізмів впливу дефіциту вітамі-ну D на суглобовий хрящ увага дослідників була звер-нена на рецептори до вітаміну D (VDR) у хондроци-тах [14,24]. Встановлено, що в нормальному хрящі гіпертрофовані хондроцити слабо експресують VDR, а в хондроцитах, які проліферують, VDR відсутні [25], але в суглобовому хрящі при остеоартрозі VDR були присутні в хондроцитах усіх зон, з максимальним пі-ком у поверхневій зоні [26].…”
Section: фактори ризику дефіциту вітаміну D і розвиток патології на тunclassified