Vitamin D status and optimal supplementation in institutionalized adults with intellectual disability

Kilpinen-Loisa, Päivi; Arvio, Maria; Ilvesmäki, Vesa; Mäkitie, Outi

doi:10.1111/j.1365-2788.2009.01218.x

Cited by 23 publications

(10 citation statements)

References 39 publications

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“…Although numerous studies such as these have investigated treatment of low BMD in children [37–40], relatively few studies have included adults. Since vitamin D levels are essential for normal skeletal mineralization and bone metabolism, vitamin D status was evaluated in institutionalized adults with ID in an open label trial [41]. This study compared oral and intramuscular (IM) administration of vitamin D in 138 Finnish adults with ID.…”

Section: Prevention and Treatment Of Low Bmd In Adults With D/idmentioning

confidence: 99%

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Aging and Bone Health in Individuals with Developmental Disabilities

Jasien

Daimon

Maudsley

et al. 2012

International Journal of Endocrinology

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Low bone mass density (BMD), a classical age-related health issue and a known health concern for fair skinned, thin, postmenopausal Caucasian women, is found to be common among individuals with developmental/intellectual disabilities (D/IDs). It is the consensus that BMD is decreased in both men and women with D/ID. Maintaining good bone health is important for this population as fractures could potentially go undetected in nonverbal individuals, leading to increased morbidity and a further loss of independence. This paper provides a comprehensive overview of bone health of adults with D/ID, their risk of fractures, and how this compares to the general aging population. We will specifically focus on the bone health of two common developmental disabilities, Down syndrome (DS) and cerebral palsy (CP), and will discuss BMD and fracture rates in these complex populations. Gaining a greater understanding of how bone health is affected in individuals with D/ID could lead to better customized treatments for these specific populations.

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Section: Prevention and Treatment Of Low Bmd In Adults With D/idmentioning

confidence: 99%

“…The plasma PTH levels decreased in both groups. This study demonstrated that vitamin D insufficiency is common in adults with ID and that either oral or intramuscular administration of vitamin D can increase mean S-25-OHD levels without adverse effects [41]. …”

Section: Prevention and Treatment Of Low Bmd In Adults With D/idmentioning

confidence: 99%

Aging and Bone Health in Individuals with Developmental Disabilities

Jasien

Daimon

Maudsley

et al. 2012

International Journal of Endocrinology

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“…recommendations are to give cholecalciferol by mouth, on a daily basis, at a dose between 700 and 1000 IU [10,11]. A range of other dosages, tested in the search for regimens that would be more convenient and improve treatment adherence, are summarised in Table 3 [12][13][14][15][16][17][18][19]9].…”

Section: Discussionmentioning

confidence: 99%

Assessment of Vitamin D Supplementation in People with Intellectual Disability

Zabalza¹,

Múgica²,

Sistiaga³

et al. 2014

J. Intellect. Disabl. Diagn. Treat.

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Vitamin D levels are often lower than recommended among certain groups, and these so-called at risk populations include institutionalised people with intellectual disabilities. The administration of vitamin D supplements does normalize these levels, but they tend to fall again when treatment is discontinued. The objectives of this study were, first, to assess whether the administration of 20,000 IU of cholecalciferol monthly and 60,000 IU quarterly over a year provide similar satisfactory results, and second, to explore whether the results are associated with following variables: sex, antiepileptic medication, being a wheelchair user or able to walk, and being a resident or day care user. The study population was composed of 204 individuals of both sexes cared for in four centres of the same institution. There were no differences between the levels reached with monthly and quarterly administration. The overall results show that, at the end of the test period, total 25(OH)vitamin D levels were <30 nmol/L in 3.5% of participants, 30 to < 50 nmol/L in 34%, 50 to <75 nmol/L in 41% and 75 nmol/L in 21.5%. There were significant differences between centres. We did not observe any harmful adverse effects attributable to the treatment. To conclude, we propose the continuous systematic administration of 60,000 IU of cholecalciferol every three months in this at-risk population.

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“…Consumption of at least 400 IU vitamin D orally a day, and at least 1,000 mg/day of calcium (50), antioxidants (51), and phytochemicals (52) increases capacity for physical exercises (53). …”

Section: Physical Health Promotion Prevention and Down Syndromementioning

confidence: 99%

Health Promotion and Disease Prevention Strategies in Older Adults with Intellectual and Developmental Disabilities

Carmeli

Imam

2014

Front. Public Health

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The rapid growth in the number of individuals living with intellectual and developmental disabilities (IDD) along with their increased longevity present challenges to those concerned about health and well-being of this unique population. While much is known about health promotion and disease prevention in the general geriatric population, far less is known about those in older adults with IDD. Effective and efficient health promotion and disease prevention strategies need to be developed and implemented for improving the health and quality of life of older adults living with IDD. This is considered to be challenging given the continued shrinkage in the overall health care and welfare system services due to the cut in the governmental budget in some of the western countries. The ideal health promotion and disease prevention strategies for older adults with IDD should be tailored to the individuals’ health risks, address primary and secondary disease prevention, and prevent avoidable impairments that cause premature institutionalization. Domains of intervention should include cognitive, mental and physical health, accommodations, workplace considerations, assistive technology, recreational activities, and nutrition.

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Vitamin D status and optimal supplementation in institutionalized adults with intellectual disability

Cited by 23 publications

References 39 publications

Aging and Bone Health in Individuals with Developmental Disabilities

Aging and Bone Health in Individuals with Developmental Disabilities

Assessment of Vitamin D Supplementation in People with Intellectual Disability

Health Promotion and Disease Prevention Strategies in Older Adults with Intellectual and Developmental Disabilities

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