Vitamin D status and its dietary and lifestyle factors in children during the first 5 years of life: A cross‐sectional multicentre Jiangsu bone study

Abstract

Background To explore the vitamin D status with its demographic and lifestyle factors including dietary, supplementation, and physical activity in 0–5 years old children. Methods This was a large population‐based cross‐sectional multicentre study in which the children were recruited from 12 Children’s Health Care Centers by a stratified cluster random‐sampling method in 10 cities in Jiangsu Province, China. Results A total number of 5289 children were investigated. The prevalence of vitamin D deficiency was 30.1%. The concentration of 25 hydroxyvitamin D was 64.0 (46.3–83.0) nmol mL−1 after adjustment for covariates. Children with higher risk of vitamin D deficiency were more likely to be at older age, girls, survey conducted in spring, location in southern Jiangsu province, residence in urban, outdoor activity < 2 h day−1 (all p < 0.05). Moreover, those with lower risk were more likely to be the number of parity ≥ 2 times, vitamin D supplementation from birth to 6 months, the initial time of vitamin D supplementation after birth ≤ 1 months, vitamin D and calcium supplementation in the last 3 months, and dose of vitamin D supplementation > 400 IU day−1 (all p < 0.05). Children with preferences for sweets, meat consumption > 150.0 g day−1, milk consumption < 250 mL day−1, time of sleeping < 10 h day−1 had higher risks of vitamin D deficiency. However, these relationships were affected by demographics. Conclusions Vitamin D status during the first five years of life was suboptimal and was associated with demographic and lifestyle determinants including milk, meat, sweets, vitamin D and calcium supplementation, sleeping and outdoor activity.

The Role of Vitamin D in Sleep Disorders of Children and Adolescents: A Systematic Review

“…Valtuerna et al [78] and Zhao et al [79], evaluated the factors associated with vitamin D deficiency in adolescents and preschool children and found out that sleep duration was one of the most relevant factors associated with vitamin D serum levels. Valtuerna et al [78] examined 1006 European adolescents (aged 12.5-17.5 years) in a multicenter study measuring body composition, biochemical marker, socioeconomical status, dietary intake, physical activity, fitness, sleep time, and vitamin D genetic polymorphism in a stepwise multivariate linear regression analysis stratified by gender.…”

“…In the Jiangsu Bone Health Study, Zhao et al [79] assessed the vitamin D status with its demographic and lifestyle factors in 5289 children during the first 5 years of life in a population-based cross-sectional multicenter study in China. The prevalence of vitamin D deficiency was 30.1%.…”

Mycophenolic Acid Exposure Optimization Based on Vitamin D Status in Children with Systemic Lupus Erythematosus: A Single-Center Retrospective Study

“…Besides the exposure levels of MPA, other factors were also associated with the variance of 25(OH)D, including age, sex, season at measurement, glucocorticoid daily dose, and use of vitamin D 3 supplements and VDRAs. Age and glucocorticoid daily dose were negatively associated with 25(OH)D, while male sex, summer [9,[36][37][38]. One large population-based multicenter study in Jiangsu Province of China investigated 5289 children and revealed that children of older age and being a girl were at a higher risk of vitamin D deficiency [36].…”

“…Age and glucocorticoid daily dose were negatively associated with 25(OH)D, while male sex, summer [9,[36][37][38]. One large population-based multicenter study in Jiangsu Province of China investigated 5289 children and revealed that children of older age and being a girl were at a higher risk of vitamin D deficiency [36]. In our study, boys with SLE had about fivefold higher 25(OH)D levels than girls with SLE (B = 5.958, P \ 0.001) and increased age was associated with decreased 25(OH)D concentrations (B = -0.959, P \ 0.001).…”

Reflections on a decade as Editor

“…Although some journals can specialise in a particular area (e.g., the Journal of Parenteral and Enteral Nutrition, or Alimentary Pharmacology and Therapeutics), JHND must navigate through much broader waters and consider research from all points in our discipline. As such, we bring together quantitative 20,21 and qualitative 22,23 research that can have direct clinical practice implications, or which is more suited to a purely academic audience. We are the official journal of the British Dietetic Association and we take particular pride in publishing the work of practising clinicians.…”