Vitamin D status among patients visiting a tertiary care center in Riyadh, Saudi Arabia: a retrospective review of 3475 cases

Alfawaz, Hanan; Tamim, Hani; Alharbi, Shmeylan; Aljaser, Saleh; Tamimi, Waleed

doi:10.1186/1471-2458-14-159

Cited by 51 publications

(38 citation statements)

References 47 publications

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“…Similar lab data-based study was carried out in neighbouring countries like India, Pakistan and Saudi Arabia. [20][21][22][23] 20 Similar large study from Pakistan involving 60,937 specimens revealed prevalence of vitamin D deficiency, defined as serum 25(OH)D <20 ng/mL to be 66.1%. 21 Smaller study with identical design found the prevalence of vitamin D deficiency (<20 ng/mL) and insufficiency (20-29.9 ng/mL) to be 60% and 27.6%, respectively.…”

Section: Discussionmentioning

confidence: 99%

Vitamin D status in Bangladeshi subjects: a laboratory based study

Islam

Hasan²,

Rahman

et al. 2019

Birdem Med J

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Background: Vitamin D plays important role in normal functioning of multiple organs of the body. Hypovitaminosis D is known to be prevalent worldwide including the tropical countries. The present study was carried out to evaluate the vitamin D status in Bangladeshi patients undergoing laboratory investigation for vitamin D. Methods: This was a laboratory-based study. Data were extracted from the database of a diagnostic centre of Dhaka city and were analysed. Vitamin D status was defined as follows: deficiency 0 to <20 ng/ml, insufficiency 20 to <30 ng/ml, sufficiency 30-100 ng/ml and potential toxicity >100 ng/ml. Results: A total of 793 plasma vitamin D level reports were analysed. Out of 793 subjects, 269 (33.9%) were male and 524 (66.1%) were female. Majority (62.0%) were between 21 and 60 years of age. Mean (+/- standard deviation) vitamin D level of the study subjects was 21.66 (+/- 18.63) ng/ml. Eighty-six percent had hypovitaminosis D; 61.4% had deficiency and 24.1% had insufficiency. Vitamin D level was found sufficient in 13.1% subjects. Among the deficient subjects, 31.6% were male and 68.4% were female; among the insufficient subjects, 35.1% were male and 64.9% were female. Sixty-eight percent of the deficient subjects belonged to the 21 to 60 year age group, whereas 57.1% of the insufficient subjects were between 21 and 60 years. Conclusion: Hypovitaminosis D is common among the real-world clinical subjects undergoing vitamin D estimation in Bangladesh. Middle-aged females are more likely to be affected Birdem Med J 2019; 9(3): 202-206

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Section: Discussionmentioning

confidence: 99%

Vitamin D status in Bangladeshi subjects: a laboratory based study

Islam

Hasan²,

Rahman

et al. 2019

Birdem Med J

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“…To our knowledge, no previous studies among Saudi adults have been carried out that focused on the relationship between vitamin D status and the risk of CHD. In Saudi Arabia, vitamin D deficiency is highly prevalent, even though there is plentiful sunlight throughout the year [17,18,19,20,21,22,23]. Several studies have reported low levels of vitamin D ranging from 8.4 to 11.6 ng/mL and from 8 to 16.6 ng/mL in males and females, respectively [17,18,22,23,24].…”

Section: Introductionmentioning

confidence: 99%

Association between Vitamin D Status and Coronary Heart Disease among Adults in Saudi Arabia: A Case-Control Study

et al. 2016

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Recent evidence has pointed out an association between vitamin D deficiency and coronary heart disease (CHD). Due to the growing epidemic of CHD and vitamin D deficiency in Saudi Arabia, exploring the role of vitamin D in the prevention of CHD is crucial. The aim of this study was to examine the association between vitamin D status and CHD in Saudi Arabian adults. This case-control study included 130 CHD cases and 195 age-sex matched controls. Study subjects were recruited from three hospitals in the western region of Saudi Arabia. Study participants were interviewed face-to-face to collect data on their socio-demographic characteristics and family history of CHD. Fasting blood samples were collected, and serum levels of vitamin D, glucose, and total cholesterol were measured. Body weight, height, and blood pressure measurements were also recorded. Severe vitamin D deficiency (25(OH)D < 10 ng/mL) was much more prevalent in CHD cases than in controls (46% and 3%, respectively). The results of multivariate logistic regression showed that vitamin D deficiency (25(OH)D < 20 ng/mL) was associated with CHD, with an odds ratio of 6.5 (95% CI: 2.7–15, p < 0.001). The current study revealed that vitamin D deficiency is independently associated with CHD, suggesting an important predictor of CHD among Saudi adults.

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“…Moreover, the prevalence of vitamin D deficiency was associated with age, and obesity, and positively correlated with calcium, albumin, and phosphorus. It was negatively correlated with alkaline phosphatase and PTH levels (16). This present study showed a higher prevalence of vitamin D deficiency among the Saudi population in Al-Madinah Al-Munawarah (91%) than what was reported by Alfawaz et al (2014) in Riyadh (72.4.1% in males).…”

Section: Discussionmentioning

confidence: 99%

“…It was negatively correlated with alkaline phosphatase and PTH levels (16). This present study showed a higher prevalence of vitamin D deficiency among the Saudi population in Al-Madinah Al-Munawarah (91%) than what was reported by Alfawaz et al (2014) in Riyadh (72.4.1% in males). Furthermore, this present study has not only detected the prevalence of vitamin D deficiency among the Saudi population, but also compared the high prevalence with those of the non-Saudi population living in the same environment via a prospective study design.…”

Section: Discussionmentioning

confidence: 99%

“…Similar results were found in other, studies that were conducted in various places in KSA. Two studies that were conducted in Riyadh indicated that vitamin D deficiency among Saudi men was 87.8% (15), and;78.1% in Saudi females and 72.4% in Saudi males respectively (16). In Damam the prevalence of vitamin D deficiency was found to be greater than 65% (17).…”

Section: Introductionmentioning

confidence: 99%

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The prevalence of vitamin D deficiency between Saudis and non-Saudis in Al-Madinah Al-Munawarah a cross-sectional study

Nasr

Othman

Hassan

et al. 2019

Preprint

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BackgroundVitamin D, or the “sunshine” hormone became an attractable topic that recently captivates many researchers. The increased prevalence of vitamin D deficiency became an alarming health concern despite the accumulative evidence exploring its crucial role not only in bone metabolism, but also in a variety of pleiotropic functions throughout the various body organs. The aim of this study is to compare the prevalence that might influence vitamin D deficiency among Saudi and non-Saudi nationalities in Almadinah Almunawarh, Saudi Arabia, and to study the different factors that may have an influence in the difference of this prevalence like the marital status, occupation, smoking, sunlight exposure, education, and dietary habits.MethodsThe study was a cross sectional study done in the medical care unit in Taiba University Almadina Almunawarah in which, 65 healthy male individuals from different nationalities (Saudis and non-Saudis), aged 18 - 65 years were divided into 2 groups, 33 Saudis and 32 non-Saudis. A sociodemographic questionnaire was filled by the study participants and 25-OH vitamin D3 (25(OH)D3) concentrations were detected by electrochemiluminescence immunoassay.ResultsResults showed a Significant percentage of the participants in the Saudi group (n = 30, 91%) suffered from deficiency in vitamin D levels [25 (OH) D < 20 ng/ml] 12.57 ± 4.82 (mean ± SD), compared to only 47% (n = 15) in the non-Saudi group [21.56 ± 6.82 (mean ± SD)]. Vitamin D deficiency was found to be significantly higher in the Saudi group than the non-Saudi group with P = 0.001.ConclusionResults showed a significant increase in vitamin D deficiency in Saudi population than the non-Saudis P = 0.001. The occupation status was found to be the only factor positively correlated with vitamin D deficiency.

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Vitamin D status among patients visiting a tertiary care center in Riyadh, Saudi Arabia: a retrospective review of 3475 cases

Cited by 51 publications

References 47 publications

Vitamin D status in Bangladeshi subjects: a laboratory based study

Vitamin D status in Bangladeshi subjects: a laboratory based study

Association between Vitamin D Status and Coronary Heart Disease among Adults in Saudi Arabia: A Case-Control Study

The prevalence of vitamin D deficiency between Saudis and non-Saudis in Al-Madinah Al-Munawarah a cross-sectional study

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