Vitamin D Levels of Anesthesia Personnel, Office Workers and Outdoor Workers in Ankara, Turkey

Erden, Gönül; Özdemir, Şerife; Öztürk, Güler; Erden, Arzu; Kara, Duygu; Işık, Serhat; Ergil, Jülide; Vural, Çağıl; Ae, Arzuhal

doi:10.7754/clin.lab.2015.151003

Cited by 7 publications

(8 citation statements)

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“…Demir et al reported an association between 25(OH)D and coronary artery ectasia, and our results are partly consistent with their results in terms of the lower level of 25(OH)D in patients with CAE [16]. In our study, we found that 25(OH)D levels were low in both groups, which is consistent with other studies in our population [17, 18]. …”

Section: Discussionsupporting

confidence: 93%

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Is there any association between vitamin D levels and isolated coronary artery ectasia?

Ciftci¹,

Çağlar²,

Bıyık

et al. 2016

Arch Med Sci Atheroscler Dis

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Introduction: It has been postulated that low vitamin D levels are associated with coronary artery diseases. Coronary artery ectasia (CAE) is associated with atherosclerosis, congenital cardiac defects, immunological diseases and connective tissue diseases. In this study, we aimed to investigate whether there is an association between vitamin D and parathormone levels and isolated coronary artery ectasia and its extent. Material and methods: The study included 93 participants: 47 patients (35 male, 12 female) with isolated CAE and 46 subjects (28 male, 18 female) with normal coronary arteries. Demographic characteristics of patients and controls were obtained from medical records, and Markis scores of patients were calculated. Serum vitamin D and parathormone levels were quantitatively measured by the paramagnetic particle chemiluminescence method. Results: Serum vitamin D levels were found to be significantly lower in patients with isolated CAE than the control group (9.15 ±4.4 ng/ml, 13.35 ±5.9 ng/ml, p < 0.001). Parathormone levels were significantly higher in the CAE group than the control group (61.4 ±31.6, 48.7 ±25.5, p < 0.036). However, the study revealed no association between serum vitamin D levels and the extent of CAE according to the Markis classification (p = 0.23). Conclusions: This study revealed that lower vitamin D levels and higher parathormone levels were associated with isolated CAE, but there was no association between vitamin D levels and the extent of CAE.

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Section: Discussionsupporting

confidence: 93%

“…They compared healthy people with normal levels of 25(OH)D to patients with CAE. However, 25(OH)D levels are generally low in our population [17, 18]. Also, they did not study the association between 25(OH)D levels and the extent of CAE.…”

Section: Introductionmentioning

confidence: 87%

Is there any association between vitamin D levels and isolated coronary artery ectasia?

Ciftci¹,

Çağlar²,

Bıyık

et al. 2016

Arch Med Sci Atheroscler Dis

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“…Exposure to sunlight for ~20 min per day is considered to maintain sufficient levels of vitamin D (15,16). However, all participants in the present study worked in a laboratory during typical sunlight hours (~8 a.m. to 6 p.m.), and thus their sunlight exposure was minimal, which was the probable cause for their vitamin D deficiency, and is in accordance with previous studies (19,20). Roomi et al (18) concluded that indoor occupations were associated with hypovitaminosis D, and a later study on coal mine workers identified vitamin D deficiency and insufficiency among the participants (21).…”

Section: Discussionsupporting

confidence: 78%

Efficacy of high dose vitamin D supplementation in improving serum 25-hydroxyvitamin D among laboratory personnel working at the Nepal National Center for Rheumatic Diseases

Giri¹,

Upreti²,

Joshi³

et al. 2017

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Abstract. Vitamin D deficiency is a highly prevalent condition worldwide. However, few studies have been conducted to examine the vitamin D status of laboratory personnel and the correlation between vitamin D deficiency and working conditions. The aim of the present study was to assess changes in serum 25-hydroxyvitamin D [25(OH)D] concentration with a weekly dose of oral cholecalciferol (60,000 IU) for two months. The prospective, open-label, interventional study was conducted from January 2016 to March 2016 at the National Centre for Rheumatic Diseases, Kathmandu, Nepal. The serum level of 25(OH)D in 19 healthy laboratory volunteers was measured at baseline and following the 2-month regimen with cholecalciferol supplement at 60,000 IU (1,500 µg)/week in oral tablet form. At baseline the mean serum 25(OH)D level was 10.31±7.78 ng/ml, which was increased following completion of the course of oral cholecalciferol to 59.78±14.74 ng/ml. This difference in the mean serum level of 25(OH)D compared with baseline was significant to P<0.001. These results indicate that vitamin D deficiency is prevalent among laboratory workers, and that high dose vitamin D3 (60,000 IU cholecalciferol) in tablet form may be effective in achieving sufficient serum 25(OH)D among laboratory personnel who tend to have lower baseline serum 25(OH)D. In conclusion, vitamin D deficiency may be common among laboratory workers, and guidelines should be formulated to implement vitamin D supplementation among laboratory personnel, as well as indoor workers, in Nepal.

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“…We believe that more comprehensive studies with more patients are needed in this area. Studies showing that muscle weakness due to vitamin D deficiency, especially in proximal muscles and vitamin D supplementation have improved and constitute the main supporting base of our study [20][21][22]. Therefore, we can foresee that the muscle relaxation reversal agent can be affected by the mode of action and the reverse duration of vitamin D levels instead.…”

Section: Discussionmentioning

confidence: 78%

The effect of vitamin D status on different neuromuscular blocker agents reverse time

Yorulmaz¹,

Demiraran²,

Özlü³

et al. 2020

Turk J Med Sci

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Background/aim This study is aimed to investigate the effects of vitamin D levels on sugammadex and neostigmine reversal times. Material and methods Eighty patients between the ages of 18 and 65 years, with ASA I-III status who were undergoing surgery under general anesthesia were included in the study. A double blind fashion was used to randomly divide all the patients into two groups. At the end of the operation, sugammadex 2 mg/kg was administered to one group (Group sugammadex) and atropine and neostigmine was administered to the other group (Group neostigmine) intravenously. In the data analysis stage, the group was divided into two subgroups according to sugammadex and group neostigmine in itself, with vitamin D levels above and below 30 ng/mL. Statistical analysis was performed on these 4 groups (Group neostigmine and vitamin D < 30 ng/mL), (Group neostigmine and vitamin D ≥ 30 ng/mL), ( Group sugammadex and vitamin D < 30 ng/mL), (Group sugammadex and vitamin D ≥ 30 ng/mL).When two responses to train of four (TOF) stimulation were taken, the following times were recorded until extubation phase. The time until TOF value 50%, 70%, 90%, and extubation were recorded. Results There were statistically significant differences between Group sugammadex and vitamin D < 30 ng/mL and Group sugammadex and vitamin D ≥ 30 ng/mL (P = 0.007) for extubation times and 50% TOF reach times (P = 0.015). However, there was no difference observed between Group neostigmine and vitamin D < 30 ng/mL and Group neostigmine and vitamin D ≥ 30 ng/mL (P = 0.999). Conclusion Vitamin D deficiency is important for anesthesiologists in terms of muscle strength and extubation time. Vitamin D deficiency seems to affect sugammadex reverse times but seems not to affect neostigmine reverse times. This conclusion needs further studies.

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Vitamin D Levels of Anesthesia Personnel, Office Workers and Outdoor Workers in Ankara, Turkey

Cited by 7 publications

References 0 publications

Is there any association between vitamin D levels and isolated coronary artery ectasia?

Is there any association between vitamin D levels and isolated coronary artery ectasia?

Efficacy of high dose vitamin D supplementation in improving serum 25-hydroxyvitamin D among laboratory personnel working at the Nepal National Center for Rheumatic Diseases

The effect of vitamin D status on different neuromuscular blocker agents reverse time

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