Vitamin D levels in white coat and sustained hypertension

Alpsoy, Şeref; Akyüz, Aydın; Akkoyun, Dursun Çayan; Gür, Demet Özkaramanlı; Topçu, Birol; Tülübaş, Feti

doi:10.1097/mbp.0000000000000171

Cited by 2 publications

(11 citation statements)

References 27 publications

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“…Many authors have stated that a decrease in vitamin D levels increases the risk of HT [ 1 – 2 ]. However, results of studies that investigated the relationship between vitamin D levels and BP in HT patients are conflicting [ 8 – 11 ]. Some studies have reported higher levels of vitamin D in HT patients as compared with NT subjects [ 8 , 9 ].…”

Section: Discussionmentioning

confidence: 99%

“…However, results of studies that investigated the relationship between vitamin D levels and BP in HT patients are conflicting [ 8 – 11 ]. Some studies have reported higher levels of vitamin D in HT patients as compared with NT subjects [ 8 , 9 ]. In these studies, an inverse association between vitamin D levels and BP was found [ 8 , 9 ].…”

Section: Discussionmentioning

confidence: 99%

“…It is well known that primary hyperparathyroidism is associated with established HT and that parathyroidectomy significantly reduces blood pressure (BP) [ 6 , 7 ]. In addition, the association between BP and serum vitamin D and PTH levels has been widely studied [ 8 – 11 ]. While some authors reported an association between BP, serum vitamin D and PTH levels [ 8 , 9 ], others did not find any relation [ 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

“…In addition, the association between BP and serum vitamin D and PTH levels has been widely studied [ 8 – 11 ]. While some authors reported an association between BP, serum vitamin D and PTH levels [ 8 , 9 ], others did not find any relation [ 10 , 11 ]. Almost all of these investigations were conducted on HT patients who were receiving antihypertensive treatment [ 8 – 11 ].…”

Section: Introductionmentioning

confidence: 99%

“…While some authors reported an association between BP, serum vitamin D and PTH levels [ 8 , 9 ], others did not find any relation [ 10 , 11 ]. Almost all of these investigations were conducted on HT patients who were receiving antihypertensive treatment [ 8 – 11 ]. One study showed that use of furosemide and dihydropyridine calcium-channel blockers was associated with higher PTH levels [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

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Association of parathyroid hormone and vitamin D with untreated hypertension: Is it different in white-coat or sustained hypertension?

et al. 2017

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BackgroundPrevious reports about the relationship between a high parathyroid hormone (PTH) and low vitamin D levels with blood pressure in different hypertension groups are conflicting.ObjectiveWe studied serum PTH and vitamin D levels in white-coat (WCHT) and sustained hypertension (SHT) patients who had not been on antihypertensive treatment. We also investigated the association between serum PTH and vitamin D levels with respect to blood pressure in SHT and WCHT patients.MethodsWe included 52 SHT patients (54.06 ± 9.2 years, 32 newly diagnosed and 20 previously diagnosed with SHT who had not been treated with antihypertensive medication for 3 months or more), 48 WCHT patients (53.64 ± 9.5 years), and 50 normotensive (NT) healthy controls (53.44 ± 8.4 years) in our study. In addition to routine tests, PTH and vitamin D levels were measured.ResultsSerum PTH levels were significantly higher in SHT patients not taking antihypertensive medications than in WCHT patients and NT controls (p = 0.004). Although PTH levels were higher in WCHT than in NT groups, the difference was not statistically significant. In SHT patients, PTH levels showed a positive correlation with office systolic (r = 0.363, p = 0.008), office diastolic (r = 0.282, p = 0.038), home systolic (r = 0.390, p = 0.004), and home diastolic blood pressures (r = 0.397, p = 0.003). Serum vitamin D levels were similar in SHT, WCHT and NT groups. Vitamin D levels were not associated with blood pressures in the entire study group. Furthermore, no significant relation was found between vitamin D and PTH levels in SHT and WCHT groups.ConclusionPTH levels are significantly higher in untreated SHT patients than WCHT patients and NT subjects. However, vitamin D levels are similar in SHT, WCHT and NT groups. There is a significant association between PTH levels and blood pressures suggesting PTH has a role in increase of blood pressure in SHT.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Association of parathyroid hormone and vitamin D with untreated hypertension: Is it different in white-coat or sustained hypertension?

et al. 2017

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Association Between Vitamin D Level and Essential Hypertension

SINGLA,

PATIL,

PATEL

et al. 2023

Asian J Pharm Clin Res

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Introduction: There is relationship between vitamin D deficiency and hypertension (HTN). The mechanism causing the development of HTN, the Renin Aldosterone Angiotensin System, was discovered to be strongly inhibited by vitamin D. This study was piloted to assess the role of vitamin D deficiency in the development of essential hypertension (EH). Methods: A total of 50 patients with EH and 50 healthy participants participated in this study. Every participant was subjected to clinical history, physical examination, and other necessary blood testing, electrocardiography, and echocardiography. Results: There was a significant decrease in vitamin D in hypertensive group (20.25±3.28 ng/mL) than normotensive group (38.33±6.89 ng/mL). Vitamin D level was moderately negative correlated with systolic blood pressure (BP) (r – 0.43, p – 0.001), strong negative correlation with diastolic BP (r – 0.76, p<0.001), strong negative correlation with intimal thickness (r – 0.67, p<0.001), and moderate negative correlation with ventricular mass (r – 0.48, p<0.001). Intimal thickness and ventricular mass were significantly higher in patients with EH with low vitamin D than those with normal vitamin D levels. Conclusion: There is a strong inverse relationship between serum vitamin D and HTN. Vitamin D deficiency levels are considered an additional risk factor for cardiovascular morbidity and mortality.

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Vitamin D levels in white coat and sustained hypertension

Cited by 2 publications

References 27 publications

Association of parathyroid hormone and vitamin D with untreated hypertension: Is it different in white-coat or sustained hypertension?

Association of parathyroid hormone and vitamin D with untreated hypertension: Is it different in white-coat or sustained hypertension?

Association Between Vitamin D Level and Essential Hypertension

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