Vitamin D Deficiency Is Associated With an Increased Likelihood of Incident Depression in Community-Dwelling Older Adults

Briggs, Robert; McCarroll, Kevin; O’Halloran, Aisling; Healy, Martin; Kenny, Rose Anne; Laird, Éamon

doi:10.1016/j.jamda.2018.10.006

Cited by 30 publications

(25 citation statements)

References 41 publications

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“…A longitudinal study with middle-aged adults in England has shown that socially isolated individuals may be less likely to perform moderate to vigorous physical activities weekly, consistently consume five daily fruits and vegetables, and are more likely to smoke [23]. Additionally, Briggs et al demonstrated that sedentary behavior is associated with having a social network, loneliness, and chronic physical conditions in middle-aged and older adults [25]. The findings of these previous studies are consistent with the findings of the present study.…”

Section: Discussionmentioning

confidence: 99%

The Influence of Social Isolation on the Preventive Behaviors for Non-Communicable Diseases in Community-Dwelling Older Adults in Japan

Yamaguchi

Yamada

Hapsari

et al. 2020

IJERPH

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This study aimed to examine the relationship between one’s physical status related to non-communicable diseases (NCDs) and social isolation, and to identify lifestyle behaviors for the prevention of NCDs associated with social isolation among community-dwelling older adults in Japan. A cross-sectional study was conducted to investigate lifestyle behaviors for NCD prevention associated with social isolation in Japanese adults aged 60 years and above in a community setting. Out of 57 participants, 17.5% were not socially participative, 66.7% hardly ever, 29.8% sometimes, and 3.5% often felt loneliness. Non-social participation and loneliness were negatively related to the frequency of vegetable and fruit intake. Additionally, loneliness was positively associated with one’s duration of smoking and current smoking habits, and negatively associated with the frequency of moderate-intensity activities, with marginal significance. Those with non-social participation or loneliness were less likely to eat a healthy diet and live a smoke-free lifestyle. The findings of this study suggest that a mutual health support system in the community and the development of community-based approaches for the prevention of NCDs among Japanese older adults are needed.

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Section: Discussionmentioning

confidence: 99%

The Influence of Social Isolation on the Preventive Behaviors for Non-Communicable Diseases in Community-Dwelling Older Adults in Japan

Yamaguchi

Yamada

Hapsari

et al. 2020

IJERPH

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“…Furthermore, vitamin D deficiency can lead to muscle weakness and may increase the risk of falls and fractures [2]. More recently, research has demonstrated associations with chronic conditions such as diabetes [3], inflammation [4], cardiovascular disease [5], depression [6] and cancer [7].…”

Section: Introductionmentioning

confidence: 99%

Geomapping Vitamin D Status in a Large City and Surrounding Population—Exploring the Impact of Location and Demographics

et al. 2020

Self Cite

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Vitamin D status was assessed in a large urban area to compare differences in deficiency and to geomap the results. In total, 36,466 participants from 28 geographical areas were identified in this cross-sectional, retrospective analysis of general practitioner (GP)-requested 25(OH)D tests at St James’s Hospital, Dublin between 2014 and 2018. The population were community-dwelling adults, median age 50.7 (18–109 years) with 15% of participants deficient (<30 nmol/L), rising to 23% in the winter. Deficiency was greatest in younger (18–39 years) and oldest (80+ years) adults, and in males versus females (18% vs. 11%, p < 0.001). Season was the biggest predictor of deficiency (OR 4.44, winter versus summer, p < 0.001), followed by location (west Dublin OR 2.17, north Dublin 1.54, south Dublin 1.42 versus rest of Ireland, p < 0.001) where several urban areas with an increased prevalence of deficiency were identified. There was no improvement in 25(OH)D over the 5-year period despite increased levels of testing. One in four adults were vitamin D deficient in the winter, with significant variations across locations and demographics. Overall this study identifies key groups at risk of 25(OH)D deficiency and insufficiency, thus providing important public health information for the targeting of interventions to optimise 25(OH)D. Mandatory fortification may be necessary to address this widespread inadequacy.

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“…The mechanism involved include the ability of vitamin D to cause alterations in the central nervous system function by causing neuronal excitotoxicity, reducing oxidative stress and helping in the formation of specific protein and neurotransmitters. 33 Although vitamin deficiency contributed to depression, it is essential to know that depression among older adults is very common and has various etiological factors such as disturbance in sleep cycle, lower neurotransmitter levels, functional limitations, poor socioeconomic status, low diet quality, lack of social support or comorbidities such as stroke and cancer. 34,35 Thus, use of dietary supplements alone is not able to improve the score of GDS.…”

Section: Discussionmentioning

confidence: 99%

Dietary Supplement Intake and Its Association with Cognitive Function, Physical Fitness, Depressive Symptoms, Nutritional Status and Biochemical Indices in a 3-Year Follow-Up Among Community Dwelling Older Adults: A Longitudinal Study

Vanoh

Shahar

Yahya

et al. 2021

CIA

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Purpose: Use of dietary supplements by older adults has been increasing for improving micronutrient deficiencies, cognitive function, and overall health status. Thus, the objective of this secondary investigation is to explore the longitudinal association of baseline supplement intake in improving cognitive function, biochemical parameters, anthropometric variables and physical fitness among older adults. Methods: Towards Useful Aging (TUA) is a three-year longitudinal study conducted at baseline (2013)(2014) and at follow-up (2015-2017) surveys. The number of participants dropped from 2322 during baseline study to 1787 and 1560 during the 18th and 36th month follow-up, respectively. Data on socio-demography, use of dietary supplement, biochemical indices, anthropometry, cognitive function, physical fitness and depressive symptoms were obtained. Longitudinal associations were done using the linear mixed model analysis among 1285 subjects with complete data. Results: The most common vitamin and mineral supplementations consumed were multivitamin, B-complex, and calcium. Meanwhile, the herbal supplements consumed by participants were Eurycoma longifolia, Morinda citrifolia and Orthosiphon aristatus. Longitudinal analysis adjusted for multiple covariates showed improvement in both supplement users and non-users for global cognitive function, working memory, visual memory, 2-minute step test, chair stand test, chair sit and reach and time up and go test, waist circumference and hip circumference in both the supplement users and non-users. Conclusion: Our findings indicated that dietary supplement intake is not associated with cognitive function, physical fitness, nutritional status, depressive symptoms or biochemical indices since improvement in the parameters was observed among both supplement users and non-users.

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Vitamin D Deficiency Is Associated With an Increased Likelihood of Incident Depression in Community-Dwelling Older Adults

Cited by 30 publications

References 41 publications

The Influence of Social Isolation on the Preventive Behaviors for Non-Communicable Diseases in Community-Dwelling Older Adults in Japan

The Influence of Social Isolation on the Preventive Behaviors for Non-Communicable Diseases in Community-Dwelling Older Adults in Japan

Geomapping Vitamin D Status in a Large City and Surrounding Population—Exploring the Impact of Location and Demographics

Dietary Supplement Intake and Its Association with Cognitive Function, Physical Fitness, Depressive Symptoms, Nutritional Status and Biochemical Indices in a 3-Year Follow-Up Among Community Dwelling Older Adults: A Longitudinal Study

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