Vitamin D deficiency is an independent predictor of elevated triglycerides in Spanish school children

Abstract

A low serum vitamin D levels in children is associated with high triglyceride levels.

The relation of vitamin D status with metabolic syndrome in childhood and adolescence: an update

“…Also the findings from studies that examined only obese or overweight (BMI > 95th or BMI > 85th percentile) subjects (31)(32)(33)(34) were similar and did not differ from those with non-obese subjects (35)(36)(37)(38). Neither socioeconomic status nor physical activity where examined had any effect on the above findings (23,24,26,37).…”

“…From the remaining 31 studies, seven found associations between vitamin D status and at least three of the MetS components (27,28,30,33,(35)(36)(37).…”

Study on Vitamin D3 and Lipid Profile Levels in Obese Population of North India

“…(19) Photo metabolism may be the mechanism involved for this as the absence of sunlight causes squalene exposed skin to divert for cholesterol formation instead of forming 7 dehydro cholesterol and vitamin D. (20) We observed decreased levels of serum HDL-C along with decreased levels in Vitamin D 3; these findings are supported by Choi et al who reported this association starting very early in life. (21) Similar findings were observed in Russian (22) and Spanish children. (23) High level of serum triglycerides and VLDL-C and decreased Vitamin D3, observed in our study, is found consistent with studies by Cigolini et al [24] Hyponnen et al [25] and Botella-Carretero et al [26] Possible mechanism of increased level of serum triglycerides associated with hypo vitamin D3 levels could be that, Vitamin D3 leads to increase in levels of serum calcium by increasing its intestinal absorption.…”

Serum 25-hydroxyvitamin D concentrations in relation to cardiometabolic risk factors and metabolic syndrome in postmenopausal women

“…The ratio of triglycerides to HDL cholesterol is also a marker for the atherogenic effect of circulating lipids (32). Although substantial variability has been observed in the association between serum 25(OH)D and dyslipidemia (11,15,(33)(34)(35)(36)(37), the inverse association with triglycerides has been reported fairly consistently in both cross-sectional and prospective cohort studies in diverse populations (8,11,(14)(15)(16)(38)(39)(40)(41)(42). In line with these findings, we observed an inverse association between serum 25(OH)D and triglycerides as well as the triglyceride:HDL ratio.…”