Vitamin D Deficiency in Slipped Upper Femoral Epiphysis

Judd, Joseph T.; Welch, Rachel L.; Clarke, Anna; Reading, Isabel; Clarke, Nicholas

doi:10.1097/bpo.0000000000000435

Cited by 17 publications

(17 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, Judd et al. ( 2015 ) also reported that only 2 of the 27 patients in their series had a normal serum vitamin D level at the time of SCFE diagnosis. On the other hand, Arkader et al.…”

Section: Discussionmentioning

confidence: 92%

See 1 more Smart Citation

Obesity-related metabolic and endocrine disorders diagnosed during postoperative follow-up of slipped capital femoral epiphysis

et al. 2018

View full text Add to dashboard Cite

Background and purposePatients with slipped capital femoral epiphysis (SCFE) are phenotypically overweight or obese and may therefore require clinical follow-up of obesity-related disorders. We evaluated obesity-related disorders such as dyslipidemia, type 2 diabetes mellitus (DM), and vitamin-D deficiency during the postoperative period in patients with SCFE.Patients and methods51 patients who were operated and followed-up for SCFE and 62 healthy adolescents without SCFE (control group) were included in this retrospective study. Patients’ BMI, serum lipid profile (total cholesterol, LDL-C, HDL-C, triglyceride), fasting blood glucose, HbA1c, and serum vitamin D levels were evaluated.ResultsAt the time of surgery, 45 patients in the SCFE group were overweight or obese (BMI >25). At the latest follow-up, 42 patients in the SCFE group and 53 patients in the control group were overweight/obese. Abnormal serum lipid profile and ratio of total dyslipidemia were similar between the groups. 8 patients had abnormal HbA1c levels in the SCFE group and mean HbA1c levels were significantly higher in the SCFE group (p = 0.03). All patients and controls had low levels of vitamin D.InterpretationAlthough serum lipid profile and vitamin D levels were detected as similar in SCFE and control groups, the potential risk of type 2 DM identified via abnormal HbA1c levels was significantly higher in patients with SCFE. We recommend that patients diagnosed with SCFE should be considered as potential candidates for type 2 DM; thus follow-up after surgical treatment should include not only orthopedic outcomes but also evaluation of future risk for DM.

show abstract

Section: Discussionmentioning

confidence: 92%

“…According to a study analyzing the results after in situ pinning, a negative correlation was found between vitamin D levels and the fusion time in the physis line (Judd et al. 2015 ). Furthermore, Judd et al.…”

Section: Discussionmentioning

confidence: 99%

Obesity-related metabolic and endocrine disorders diagnosed during postoperative follow-up of slipped capital femoral epiphysis

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Some studies have theoretically suggested such an association. 25,26 In clinical series, some show a correlation between SCFE and vitamin D levels 27,28 whereas others show no correlation. [29][30][31][32] However, there are no definitive, large-size studies demonstrating a significant correlation between SCFE and vitamin D levels compared with the general population.…”

Section: Discussionmentioning

confidence: 99%

Slipped Capital Femoral Epiphysis, Food Deserts, Poverty, and Urban/Rural Residence: Is There a Link?

Luster

Gunderson

Sun

et al. 2022

Journal of Pediatric Orthopaedics

View full text Add to dashboard Cite

Background: Childhood obesity is increased in food deserts, a community with little to no access to healthy food. As obesity is associated with slipped capital femoral epiphysis (SCFE), it was the purpose of this study to analyze the prevalence of SCFE patients by food desert location and its interaction with rural/urban location. Methods: A retrospective review of all consecutive patients with idiopathic SCFE treated at our institution over 11 years was performed. From the patient's address, the US Census Bureau tract in which the patient resided was determined. Using the census tract code, it was ascertained if the patient lived in a food desert and urban or rural location. Standard statistical analyses were performed; a P < 0.05 was considered statistically significant. Results: There were 177 SCFE patients: 79 girls, 98 boys, 106, White, and 69 nonWhite. The average age at diagnosis was 12.1 ± 1.7 years, the average symptom duration 4.1 ± 5.1 months, and the average weight percentile 94 ± 10. Of these 177 patients, 26.5% lived in a food desert, which was higher than the expected 17.5% (P = 0.023). Those living in a food desert were more commonly nonWhite (60% vs. 32%, P = 0.0014). There were 25% from rural areas and 75% from urban areas. No rural SCFE patients lived in food deserts whereas 34% of urban patients lived in food deserts. The average poverty rate of the SCFE patient census tracts was 19%, no greater than the expected 15% (P = 0.32). SCFE patients living in rural census tracts had a lower poverty rate (P < 10 -6 ). Conclusions: There is a correlation with the prevalence of SCFE patients by residence in a "food desert", but not with rural/urban locale or poverty status in Indiana. Further research will be needed to see if these findings apply to other states within the United States and other parts of the world. Level of Evidence: III.

show abstract

“…The relationship between vitamin D levels and SCFE has been given more attention in recent decades. Although the direct mechanism by which vitamin D deficiency is related to SCFE is unknown, multiple studies have shown correlations between the two 17,18 .…”

Section: Discussionmentioning

confidence: 99%

Slipped Capital Femoral Epiphysis in an Adult with Panhypopituitarism

Rosen

Wong

Worts

et al. 2021

JBJS Case Connector

View full text Add to dashboard Cite

Case: Our patient was a 31-year-old woman with previously undiagnosed panhypopituitarism who presented with bilateral slipped capital femoral epiphysis (SCFE). Together with endocrinology, her treatment plan involved medical management of her panhypopituitarism and surgical correction with femoral neck osteotomy. Hormone deficiencies were corrected 6 weeks after replacement therapy began, and the patient was cleared for surgery. By 5 months after osteotomy, examination revealed delayed union and prominent screws bilaterally. Hardware exchange and repeat internal fixation were then performed. At 8 weeks after revision, she presented with avascular necrosis, and the decision was made to proceed with total hip arthroplasty. A 5-year follow-up period was documented. Conclusion: This case presented a rare look at SCFE in an adult patient with panhypopituitarism. Other systemic illnesses that can contribute to SCFE or other orthopaedic issues include, but are not limited to, multiple endocrine neoplasia syndromes, vitamin D deficiency, renal osteodystrophy, Kallmann syndrome, Klinefelter syndrome, and pathologies affecting the thyroid and pituitary gland.

show abstract

Vitamin D Deficiency in Slipped Upper Femoral Epiphysis

Cited by 17 publications

References 28 publications

Obesity-related metabolic and endocrine disorders diagnosed during postoperative follow-up of slipped capital femoral epiphysis

Obesity-related metabolic and endocrine disorders diagnosed during postoperative follow-up of slipped capital femoral epiphysis

Slipped Capital Femoral Epiphysis, Food Deserts, Poverty, and Urban/Rural Residence: Is There a Link?

Slipped Capital Femoral Epiphysis in an Adult with Panhypopituitarism

Contact Info

Product

Resources

About