Vitamin D Deficiency in Pregnant Women at a Tertiary Hospital in Western Sydney

Harris, A.

doi:10.15406/ogij.2017.07.00234

Cited by 5 publications

(3 citation statements)

References 20 publications

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“…The prevalence of vitamin D deficiency in this study was 14.1%. The finding is in line with several studies reported from different countries across the globe that show vitamin D deficiency prevalence ranging from 4-60% [20][21][22][23][24][25]. A previous pilot study carried out on a convenient sample of 40 parturient women at Nnamdi Azikiwe University Teaching Hospital, Nnewi Nigeria showed a vitamin D deficiency level of 7.5% [26] -almost half of our present findings.…”

Section: Discussionsupporting

confidence: 93%

Vitamin D status and its influence on pregnancy outcomes amongst pregnant women in southeastern Nigeria

Brian-D¹,

Eberendu²,

Dolly³

et al. 2020

World J. Adv. Res. Rev.

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This is a prospective cross-sectional study involving 256 consecutive consenting parturient women in southeastern Nigeria. The study aimed to determine the vitamin D levels of the pregnant women together with its influence on pregnancy outcomes. It involved assay of vitamin D levels from blood samples of the women using High Pressure Liquid Chromatography (HPLC).Vitamin D levels were analyzed in respect of the women's biodata and pregnancy outcome variables using SPSS. Data comparison was made using chi-square test and student t-test with p-values of<0.05 at 95% confidence interval considered as significant. Of the 256 pregnant women studied, 36(14.1%) had vitamin D deficiency (VDD). Mean serum vitamin D significantly decreased with increasing parity and increasing gestational age up to term (37-42 weeks). There was progressive increase in number of women (normal and vitamin D-deficient) for labour onset between 37 th and 42nd weeks. Vitamin D levels did not influence type or mode of delivery. No trend occurred between vitamin D and both antenatal and labour complications and no relationship occurred between serum vitamin D and fetal birth weight; although number of women with VDD increased with increasing placental weight. The prevalence of VDD in pregnant women in this study (14.1%), is low. There is also no associated deleterious pregnancy outcome to justify routine antenatal vitamin D supplementation, as suggested elsewhere. A larger population and multi-centered study may perhaps elucidate further the influence of vitamin D on pregnancy outcome amongst the people in this study area.

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Section: Discussionsupporting

confidence: 93%

Vitamin D status and its influence on pregnancy outcomes amongst pregnant women in southeastern Nigeria

Brian-D¹,

Eberendu²,

Dolly³

et al. 2020

World J. Adv. Res. Rev.

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“…Vitamin D deficiency is observed worldwide in pregnant women and their neonates [1][2][3][4][5]. Maternal vitamin D deficiency is associated with various problems in their babies such as preterm delivery, low birth weight, neonatal hypocalcemia etc.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of vitamin D deficiency in pregnant women and their babies in Bhaktapur, Nepal

et al. 2019

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Background: Vitamin D deficiency has been observed worldwide in pregnant women and their newborns. Maternal vitamin D deficiency can lead to deficiency in their newborn baby and has been linked with various complications during pregnancy and delivery. There is risk of premature delivery and it is associated with high neonatal mortality. Methods: Seventy-nine pregnant women who were admitted to the Siddhi Memorial Hospital for delivery and their newborn babies were enrolled in the study. Maternal blood samples were taken before delivery while umbilical cord blood samples of their babies were taken after delivery. Serum vitamin D level and calcium level were assessed by fluorescence immunoassay using Ichromax vitamin D kit and endpoint method, respectively in the Siddhi Memorial Hospital laboratory. Results: Mean +/− SD serum vitamin D and calcium levels in pregnant mother before delivery were 14.6 +/− 8.5 ng/ml and 8.0 +/− 0.5 mg/dl, respectively, and in the cord blood were 25.7 +/− 11.2 ng/ml and 8.6 +/− 0.9 mg/dl, respectively. Eighty-one percent of the mothers and 35.8% of their babies were found to have vitamin D deficiency. Although 97.5% of the pregnant women were taking calcium supplementation, serum calcium was found lower than the normal reference value in 67% of the pregnant women and 64.2% of their babies. There were a linear relationship between the maternal and baby's serum vitamin D (P < 0.001) and calcium (P < 0.001) levels. Conclusion: There is high prevalence of vitamin D and calcium deficiency in pregnant mothers and newborn babies in Bhaktapur, Nepal. Pregnant women need to be supplemented with adequate amounts of these nutrients.

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“…The main action of vitamin D is to maintain the physiological levels of serum calcium and phosphorus. The importance of vitamin D for skeletal development, modulation of calcium homeostasis, bone formation, and resorption has been well described in literature [4][5][6]. It has also other vital roles in regulation of immune function, cell growth, and inflammation in the body [4][5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Serum 25- hydroxy vitamin D levels in pregnant women with increase in parity in Tamilnadu population

Lakshmi¹,

Kumar²,

Valvekar³

2017

Obs Gyne Reivew J Obstet Gynecol

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Introduction:Prevalence of vitamin D deficiency among pregnant women is a preventable and treatable health problem. Studies on vitamin D deficiency in pregnant women reported the adverse effects on maternal health and fetal wellbeing. Utmost attention is required in prevention of vitamin D deficiency among pregnant women. Aim of the present study is to know the status of vitamin D levels in pregnant women of different gravidaand to compare biochemical parameters in pregnant women with increase in parity. Materials and Methods: This is a prospective and observational study. Estimation of serum vitamin D levels was studied in 189 pregnant women. Pregnant females were randomly selected, who attended the antenatal clinic from April 2016 to November 2017. Women with serum 25-hydroxy vitamin D level lower than 10ng/ml were diagnosed as vitamin D deficient. Results: In the present study, the mean serum 25-OH vitamin D of all pregnant women is 16.7 ± 10.5 ng/ml. Primigravida women had higher 25-OH vitamin D (15.4 ± 10.7 ng/ml) than the second and the third grvida women (10.5 ± 8.9ng/ml and 9.7 ± 7.6 ng/ml, both P<0.001). The 77% of primigravida women and 55% of second gravida women had serum 25-OH vitamin D concentrations below 10 ng/ml. Strong association was observed between low vitamin D levels and increase in parity. Conclusion: The high prevalence of vitamin D deficiency in pregnancy calls for unanimous approach to tackle this grave situation by implementing a national strategy for screening, prevention, and treatment of this deficiency.

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Vitamin D Deficiency in Pregnant Women at a Tertiary Hospital in Western Sydney

Cited by 5 publications

References 20 publications

Vitamin D status and its influence on pregnancy outcomes amongst pregnant women in southeastern Nigeria

Vitamin D status and its influence on pregnancy outcomes amongst pregnant women in southeastern Nigeria

Prevalence of vitamin D deficiency in pregnant women and their babies in Bhaktapur, Nepal

Serum 25- hydroxy vitamin D levels in pregnant women with increase in parity in Tamilnadu population

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