Vitamin D Deficiency and Pcos;

Abstract

BackgroundPolycystic ovary syndrome (PCOS) is mainstream gynaecological problems in adult women. Vitamin D has been linked to propensity of developing PCO. As this hormones has certain effects on insulin sensitivity and restoration of reproductive capacity in women with PCOs. So, a study was planned to establish correlation of deficiency of vitamin D and PCOs.ObjectiveTo determine the correlation of deficiency of vitamin D with PCOs in patients reporting to a teaching hospital.Material & MethodsCase control study carried out at institute of Shaikh Zayed Hospital, Lahore, Gynae-Obst Department for six months. If serum level of vitamin D is < 25nmol/L then deficiency was labeled. Odds ratio was calculated between PCOs and vitamin D deficiency, ResultsThe mean age of the patients was 26.91±6.09 years. In this study, 70% females were married. The mean BMI of patients was 22.59±2.48kg/m2, and 76(76%) patients had normal BMI and 24(24%) patients were overweight. Vitamin D deficiency was observed in 47 cases in which 31 were from case group and 16 were from control group with significant association i.e. OR=3.47. ConclusionOur study results concluded that there is more risk of vitamin D deficiency in females with PCOS as compared to females without PCOS.

Low Vitamin D Level in Saudi Women With Polycystic Ovary Syndrome

“…The results affirm that the vitamin D level was significantly lower in women with PCOS than in those without. This finding is in agreement with those of studies conducted in different countries (8,9,15,18,26,27). It is not consistent with that of a study of women with PCOS living in Makkah, located in the Western region, in which the vitamin D levels were similar among patients and controls (25); nonetheless, a larger study in the same region demonstrated lower levels of vitamin D in women with PCOS (17).…”

Relation of Vitamin D Deficiency in Women with Polycystic Ovarian Syndrome in Kirkuk

“…between vitamin D and cholesterol in PCOS women and control group as seen in figure (1.4). [22]. Another study showed PCOs women had more predilection to cardiovascular disease than non PCOs control (reference quote) [23].…”

“…Other study observed that most of females are vitamin D deficient but no evidence is available regarding the association of POC with vitamin D deficiency. Moreover, other literature has reported controversial results[22]. Other results suggest that vitamin D treatment might improve glucose metabolism and menstrual frequency in PCOS women[27].…”