Vitamin D deficiency and depression in adults: systematic review and meta-analysis

Anglin, Rebecca; Samaan, Zainab; Walter, Stephen D.; McDonald, Sarah D.

doi:10.1192/bjp.bp.111.106666

Cited by 657 publications

(531 citation statements)

References 56 publications

Supporting

Mentioning

443

Contrasting

Unclassified

Order By: Relevance

“…This supports previous reviews findings of general hypovitaminosis D in this patient population with one review findings 59.14% and the other 65.3% (Belvederi Murri et al, 2013;Valipour et al, 2014, respectively) and suggests that on average over half of psychotic patients are deficient of vitamin D at any one time. This is in line with research in other areas suggesting that low vitamin D is also common in other mental health disorders such as depression and anorexia (Anglin et al, 2013;Veronese et al, 2015, respectively).…”

Section: Discussionsupporting

confidence: 90%

Correlates of vitamin D in psychotic disorders: A comprehensive systematic review

Adamson

Lally

Gaughran

et al. 2017

Psychiatry Research

View full text Add to dashboard Cite

(199/ 200)People with psychosis have high prevalence of low vitamin D levels but the correlates and relevance of this deficiency are unclear. A systematic search of major databases from inception to 03/2016 was undertaken investigating correlates of vitamin D in people with psychosis. Data was summarised with a best evidence synthesis. Across 23 included studies (n=1,770 psychosis, n= 8,171 controls) a mean difference in vitamin D levels between both groups of -11.14 ng/ml 0.59 was found.

show abstract

Section: Discussionsupporting

confidence: 90%

Correlates of vitamin D in psychotic disorders: A comprehensive systematic review

Adamson

Lally

Gaughran

et al. 2017

Psychiatry Research

View full text Add to dashboard Cite

show abstract

“…The majority of these are centred on the ability of certain nutrients contained within FV to influence psychological well-being. While a number of nutrients such as n-3 PUFA (15) , vitamin B 12 (10) and vitamin D (16) have been studied with regard to psychological well-being, this review only focuses on nutrients that are found in FV, and which have shown promise in this regard.…”

Section: Proceedings Of the Nutrition Societymentioning

confidence: 99%

The potential role of fruit and vegetables in aspects of psychological well-being: a review of the literature and future directions

2013

View full text Add to dashboard Cite

The objective of the present paper was to review the literature investigating the potential relationship between fruit and vegetables (FV) and psychological well-being. The rising prevalence of mental ill health is causing considerable societal burden. Inexpensive and effective strategies are therefore required to improve the psychological well-being of the population, and to reduce the negative impact of mental health problems. A growing body of literature suggests that dietary intake may have the potential to influence psychological well-being. For example, studies have suggested that particular dietary constituents, including vitamins and minerals, might be beneficial to psychological health. However, in order to better reflect normal dietary intake, health-based research has increasingly begun to focus on whole foods and dietary patterns, rather than individual nutrients. One food group that has received increasing attention with regard to psychological health is FV. This is probably a result of the strong evidence base, which exists in relation to their protective association with a number of chronic diseases, as well as the fact that they are a rich source of some of the nutrients which have been linked to psychological health. While some promising findings exist with regards to FV intake and psychological well-being, overall, results are inconsistent. Possible reasons for this, such as methodological issues related to study design and the measurement of psychological well-being and FV intake, are discussed within this review. Based on the predominantly observational nature of existing literature, the present paper concludes that future well-designed randomised controlled trials are required to investigate the relationship further.

show abstract

“…Although there is a variation in the prevalence of depression using different tools, mental health problems namely depression are health conditions that should not be overlooked. Its consequences include impairment in functional well-being and poorer quality of life (10,11) , physical distress and health problems (12) .A systematic review by Anglin et al (13) found an increased odds/risk of depression for the lowest v. highest vitamin D categories in cross-sectional studies (OR = 1·31; 95 % CI 1·0, 1·71) as well as cohort studies (hazard ratio = 2·21; 95 % CI 1·40, 3·49). Ecemis and Atmaca (14) found that quality of life was impaired in vitamin D-deficient and -insufficient premenopausal women.…”

mentioning

confidence: 99%

Vitamin D deficiency and depression among women from an urban community in a tropical country

Moy

Hoe

Hairi

et al. 2016

Public Health Nutr.

View full text Add to dashboard Cite

Objective: To determine the association of vitamin D status with depression and health-related quality of life among women. Design: This was a cross-sectional study conducted among women in Kuala Lumpur, Malaysia. Sociodemographic characteristics, physical activity status, perceived depression and health-related quality of life were assessed via a selfadministered questionnaire. Fasting blood samples were taken for the analysis of 25-hydroxyvitamin D, parathyroid hormone, fasting blood glucose and full lipid profile. Complex samples multiple logistic regression analysis was performed. Setting: Public secondary schools in Kuala Lumpur, Malaysia. Subjects: Seven hundred and seventy female teachers were included. Results: The mean age of participants was 41·15 (95 % CI 40·51, 41·78) years and the majority were ethnic Malays. Over 70 % of them had vitamin D deficiency (<20 ng/ml or <50 nmol/l) and two-thirds were at risk for depression. In the multivariate analysis, ethnic Malays (adjusted OR (aOR) = 14·72; 95 % CI 2·12, 102·21) and Indians (aOR = 14·02; 95 % CI 2·27, 86·59), those at risk for depression (aOR = 1·88, 95 % CI 1·27, 2·79) and those with higher parathyroid hormone level (aOR = 1·13; 95 % CI 1·01, 1·26) were associated with vitamin D deficiency, while vitamin D deficiency was negatively associated with mental health-related quality of life (Mental Component Summary) scores (aOR = 0·98; 95 % CI 0·97, 0·99). Conclusions: Vitamin D deficiency is significantly associated with depression and mental health-related quality of life among women in Kuala Lumpur, Malaysia. Vitamin D deficiency is a global public health problem affecting a billion people worldwide (1) . Malaysia is a tropical country located near the equator. Being close to the equator, Malaysia enjoys abundant sunshine throughout the year. On average, Malaysia receives about 6 h of sunshine per day. With the exception of the monsoon seasons, it is extremely rare for Malaysians to have a stretch of days with completely no sunshine. However, the Malaysian population, especially the ethnic Malay and Indian women, have been found to be more susceptible to vitamin D deficiency (2,3) . The role of vitamin D is well established in Ca homeostasis and bone health (4,5) . Current evidence shows that vitamin D deficiency is also associated with increased risk for metabolic syndrome (MetS), certain types of cancer, type 2 diabetes mellitus and CVD (6,7) .Depression is one of the leading causes of disability and mortality worldwide. Globally, about 840 million people suffer from depression (8) . The National Health and Morbidity Survey (NHMS) 2011 in Malaysia reported that the prevalence of lifetime depression and current depression was 2·4 % and 1·8 %, respectively (9) , using the Mini International Neuropsychiatry Interview (MINI). Although there is a variation in the prevalence of depression using different tools, mental health problems namely depression are health conditions that should not be overlooked. Its consequences include impairment in func...

show abstract

Vitamin D deficiency and depression in adults: systematic review and meta-analysis

Abstract: Our analyses are consistent with the hypothesis that low vitamin D concentration is associated with depression, and highlight the need for randomised controlled trials of vitamin D for the prevention and treatment of depression to determine whether this association is causal.

Cited by 657 publications

References 56 publications

Correlates of vitamin D in psychotic disorders: A comprehensive systematic review

Correlates of vitamin D in psychotic disorders: A comprehensive systematic review

The potential role of fruit and vegetables in aspects of psychological well-being: a review of the literature and future directions

Vitamin D deficiency and depression among women from an urban community in a tropical country

Contact Info

Product

Resources

About