Vitamin D concentrations in an UK inner-city multicultural outpatient population

Ford, Loretta; Graham, Valerie; Wall, Alan; Berg, J. M.

doi:10.1258/000456306778904614

Cited by 70 publications

(59 citation statements)

References 24 publications

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“…This is to be expected as the association of low total 25-OH vitamin D concentrations with ethnicity has been reported elsewhere. 11,19,20 There is a statistically significant negative correlation between percentage of non-White population of an LSOA and median total 25-OH vitamin D. There is no statistically significant correlation between IMD and total 25-OH vitamin D, suggesting that the most important variable in determining total 25-OH vitamin D status is ethnicity and not economic status. This conclusion is further strengthened by the data presented in Supplementary Figure 3.…”

Section: Discussionmentioning

confidence: 95%

Relationship of total 25-OH vitamin D concentrations to Indices of Multiple Deprivation: geoanalysis of laboratory results

Webster

2012

Ann Clin Biochem

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Background: Vitamin D deficiency appears to be widespread and associated with ethnicity and economic status. Geography is the key to virtually all national statistics. It provides a structure for collecting, processing, storing and aggregating data. Linking geographic data to laboratory data allows analysis of the association of laboratory data with economic indicators. Methods: The laboratory information system was searched to create a data-set of total 25-OH vitamin D concentrations, which was then linked to economic (Indices of Multiple Deprivation [IMD]) and ethnicity data using postcodes geocoded to Lower Super Output Areas (LSOAs). Results: A total of 12422 25-OH vitamin D requests were received during the time period searched. A total of 12167 of these had associated postcodes that would allow georeferencing to LSOAs. The median total 25-OH vitamin D was 24.5 nmol/L (5.3-99.0; 2.5 -97.5th percentile). Statistically significant (Spearman rank) correlations were found between median 25-OH vitamin D (nmol/L) and percentage of non-White population and percentage of non-White population and IMD. No statistically significant correlation between median 25-OH vitamin D concentration and IMD was found; however, a statistically significant correlation between percentage of population classified as severely deficient and IMD was found. Conclusions: In summary, vitamin D deficiency is widespread and is related to ethnicity; it does not appear to be related to economic status except in cases of severe vitamin D deficiency.

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Section: Discussionmentioning

confidence: 95%

Relationship of total 25-OH vitamin D concentrations to Indices of Multiple Deprivation: geoanalysis of laboratory results

Webster

2012

Ann Clin Biochem

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“…The possible reasons for this ethnic difference include variations in skin pigmentation, sun exposure, dietary intake, genetic and cultural factors [6][7][8] .…”

Section: Discussionmentioning

confidence: 99%

“…Ethnic differences in vitamin D levels have been previously described [6][7][8][9] . In a multiethnic population-based study conducted in the United Kingdom (UK), vitamin D levels are lowest among Asians followed by Afro-Caribbeans and highest among Caucasians 6 . In another UK epidemiologic study, they found an age-adjusted prevalence rate of vitamin D deficiency (<20 μg/L) of 93% among South Asian males 9 .…”

Section: Introductionmentioning

confidence: 99%

Plasma Vitamin D Levels are Lower among Ethnic Indians in Matched Pairs of Male Acute Ischaemic Stroke Patients of Indian and Chinese Ethnicity

Silva

Talabucon

Tan

et al. 2013

Proceedings of Singapore Healthcare

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Introduction: Ethnic Indians have a high burden of vascular disease. Vitamin D deficiency is associated with an increased risk of vascular disease including ischaemic stroke. Vitamin D levels are lower among ethnic Indians compared to ethnic Chinese in healthy individuals. We compared the plasma 25-hydroxyvitamin D [25(OH)D] levels between ethnic Indians and Chinese male ischaemic stroke patients.

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“…Ford et al [25] have reported widespread vitamin D deficiency in a UK-inner city population, more so in women. The results of the present study support these reports in that females showed a higher prevalence of vitamin D deficiency than males, in the total study population as well as in all age groups.…”

Section: Citationmentioning

confidence: 99%

Prevailing Serum Vitamin D Levels among Individuals in South Karnataka

M¹,

Lasrado²,

Sg³

et al. 2017

J Bioanal Biomed

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Introduction: Prevalence of vitamin deficiency is very high in India. The aim of the present study was to determine according to age groups, the status of vitamin D among individuals using samples received at clinical biochemistry laboratory. Materials and methods:The study population was grouped according to gender and age in decades. They were divided into three groups according to serum vitamin D status-NVD (normal serum vitamin D, >30 ng/ml), VDI (vitamin D insufficiency, 20-30 ng/ml), VDD (vitamin D deficiency, <20 ng/ml). Blood was collected in plain vacutainers and serum obtained was used for vitamin D estimation. Results were expressed as percentage of the sub-population in question.Results: Only 13% of the total study population was normal, 70% was vitamin D deficient and 17% showed vitamin D insufficiency. The prevalence of vitamin D deficiency was very high in all age groups and both genders. In all age groups, there were a higher percentage of females in the vitamin D insufficient and deficient groups. Males recorded higher prevalence of vitamin D deficiency in the 0-10 and 20-30 years age group while females recorded higher prevalence of the vitamin deficiency in the 20-30 years and 30-40 years age group Conclusion:The prevalence of vitamin D insufficiency and deficiency in the present study was high at all age groups and both genders. Further research needs to be conducted to correlate the changing dietary habits to the alterations in availability of 7-dehydrocholesterol for cutaneous biosynthesis of vitamin D.

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Vitamin D concentrations in an UK inner-city multicultural outpatient population

Cited by 70 publications

References 24 publications

Relationship of total 25-OH vitamin D concentrations to Indices of Multiple Deprivation: geoanalysis of laboratory results

Relationship of total 25-OH vitamin D concentrations to Indices of Multiple Deprivation: geoanalysis of laboratory results

Plasma Vitamin D Levels are Lower among Ethnic Indians in Matched Pairs of Male Acute Ischaemic Stroke Patients of Indian and Chinese Ethnicity

Prevailing Serum Vitamin D Levels among Individuals in South Karnataka

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