Vitamin D and Sjögren syndrome

Garcı́a-Carrasco, Mario; Jiménez-Herrera, Erick Alejandro; Gálvez-Romero, José Luis; Lara, L. Vázquez de; Mendoza‐Pinto, Claudia; Etchegaray‐Morales, Ivet; Munguía‐Realpozo, Pamela; Ruı́z-Argüelles, Alejandro; Rosas, José; Vera-Recabarren, Mauricio; Cervera, Ricard

doi:10.1016/j.autrev.2017.04.004

Cited by 45 publications

(22 citation statements)

References 50 publications

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“…Whereas Cermak et al did not find a different intake of vitamin D between pSS-patients and controls [ 9 ], Erten et al found lower plasma levels of vitamin D in patients compared with controls [ 11 ]. A recent review [ 38 ] found evidence of lower vitamin D levels in pSS-patients that were associated with extraglandular manifestations, whereas another study did not [ 39 ].…”

Section: Discussionmentioning

confidence: 99%

Dietary Intake, Body Composition, and Oral Health Parameters among Female Patients with Primary Sjögren’s Syndrome

et al. 2018

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There is limited knowledge about dietary intake and body composition among patients with primary Sjögren’s syndrome. We assessed dietary intakes with 24-h recalls and body composition with anthropometry and bioelectrical impedance in 20 female patients. Various scoring tools were used to assess oral health. The patients had a lower energy percentage (E%) from carbohydrates (p = 0.02) and a higher E% from fat (p = 0.01) compared to a reference group. The lower intake of carbohydrates was due to a lower bread intake (p = 0.04), while the higher intake of fat was due to a higher intake of butter, margarine, and oil (p = 0.01). The patients ate more than twice (p = 0.02) as much fish as the reference group. The compliance to recommended intakes of macro- and micronutrients was good. Forty-percent of the patients were overweight/obese. Increased intake of beverages was observed in patients with severe xerostomia and/or low oral health-related quality of life, whereas reduced fat intake was found in hyposmic patients. In conclusion, the dietary intake among the patients was not much different from the reference group and complied with recommendations. Most oral health parameters were not associated with nutrient intakes. Specific dietary guidelines are probably not needed to ensure adequate nutrition among such patients.

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Section: Discussionmentioning

confidence: 99%

Dietary Intake, Body Composition, and Oral Health Parameters among Female Patients with Primary Sjögren’s Syndrome

et al. 2018

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“…Vitamin D (VitD) has a very well known role in bone metabolism and calcium homeostasis, having also important immunomodulatory functions [5]. Its deficiency has been linked to the pathogenesis and clinical manifestations of autoimmune diseases such as diabetes, multiple sclerosis, Crohn disease, rheumatoid arthritis, SLE or Sjögren syndrome [6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Vitamin D and antiphospholipid syndrome: A retrospective cohort study and meta-analysis

Riancho‐Zarrabeitia

Cubería

Muñoz

et al. 2018

Seminars in Arthritis and Rheumatism

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“…In addition, studies have shown that decreased ionized calcium levels in VDR deficient animals, caused the rate of corneal epi-thelial wound healing to decrease and mucin packaging in conjunctival goblet cells to be altered [14,15]. Vitamin D may play a role in Sjögren Syndrome (SS) pathogenesis and low levels of vitamin D have been found in SS patients [16]. These studies suggest that vitamin D with anti-inflammatory actions and positive effects on corneal epithelial cells and goblet cells may have relieving effects on dry eye symptoms and signs.…”

Section: Discussionmentioning

confidence: 99%

The relationship between serum vitamin D levels and dry eye syndrome in postmenopausal women

Arman¹

2020

Ann Clin Anal Med

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Aim: In this study, we aimed to investigate the association between serum vitamin D levels and dry eye signs and symptoms in postmenopausal women. Material and Method: Postmenopausal women with severe vitamin D deficiency (Group 1, n=30), moderate deficiency (Group 2, n=27) and those with optimal serum vitamin D levels (Group 3, n=30) were recruited for this cross-sectional study. Dry eye complaints were evaluated by the Ocular Surface Disease Index (OSDI) questionnaire and dry eye signs were evaluated by the Schirmer's test I, the Tear break up time (TBUT) test, and ocular surface fluorescein staining. Results: The mean vitamin D level of the Group 1 was 7.82± 1.80 ng/ml, that of the Group 2 was 15.88±1.70 ng/ml and Group 3 was 33.47±7.00 ng/ml The percentages of patients diagnosed as dry eye were 53.33% for Group 1, 44.44% for Group 2, and 33.33% for Group 3 (p₌0.29). There was no statistically significant difference between Group 1 (37.55 ± 19.20Group 2 (43.58 ±16.79), and Group 3 (40.87 ± 21.32) in respect to the mean OSDI scoresIn addition, there was no any statistically significant difference between the three groups in terms of the mean TBUT (Group 1: 7.73±3.25 secs, Group 2: 6.78±2.99 secs and Group 3: 6.70 ± 3.37 secs) and Schirmer's test I scores in (Group 1: 9.30 ± 4.86 mm, Group 2: 8.07 ± 4.09mm and Group 3: 9.40 ± 5.49mm) (p₌0.33 vs p₌0.72). Eight patients (26.7%) in Group 1, 5 patients (18.5%) in 19.20 Group 2, and 3 patients (10%) in Group 3 have positive corneal fluorescein staining (p₌0.25). Discussion: Serum vitamin D levels have no association with dry eye complaints evaluated by OSDI questionnaire and tear film deficiency and functional integrity detected by the tests in postmenopausal women.

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Vitamin D and Sjögren syndrome

Cited by 45 publications

References 50 publications

Dietary Intake, Body Composition, and Oral Health Parameters among Female Patients with Primary Sjögren’s Syndrome

Dietary Intake, Body Composition, and Oral Health Parameters among Female Patients with Primary Sjögren’s Syndrome

Vitamin D and antiphospholipid syndrome: A retrospective cohort study and meta-analysis

The relationship between serum vitamin D levels and dry eye syndrome in postmenopausal women

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