Vitamin D and health-related quality of life in a community sample of older Canadians

Abstract

PurposeTo assess how vitamin D status is associated with health-related quality of life (HRQOL) among older residents of Canada.DesignWe analysed baseline data of 1,493 Canadians aged 50 years and over in Alberta on HRQOL (EQ-5D-5L) and serum 25-hydroxyvitamin D (25(OH)D) as a measure of vitamin D status. We applied multivariable regression methods to examine the association between vitamin D status and each of the five dimensions and the summary index of the EQ-5D-5L.ResultsParticipants with higher serum 25(OH)D levels were significantly less likely to report problems with mobility, usual activities, and depression and anxiety. Specifically, age- and gender-adjusted odds ratios for reporting problems with mobility, usual activities, and depression and anxiety were 0.58 (95 % confidence interval 0.44–0.78), 0.67 (0.50–0.89), and 0.67 (0.51–0.88) per 100 nmol/L increase in 25(OH)D, respectively. No significant associations were observed for problems with self-care and with pain and discomfort. HRQOL scores combining the responses of each of the five dimensions increased significantly with increasing serum 25(OH)D levels.ConclusionsThis is the first study to reveal the importance of vitamin D for the five dimensions of HRQOL in a community-based sample. The observed associations of vitamin D and HRQOL call for intervention studies to strengthen the evidence of the potential benefits of vitamin D supplementation for HRQOL among older adults.

EQ-5D-derived health utilities and minimally important differences for chronic health conditions: 2011 Commonwealth Fund Survey of Sicker Adults in Canada

“…The MID of the EQ-5D-derived health utilities for different health conditions has been estimated in the USA and the UK [16][17][18][19]. Although the EQ-5D is being increasingly used in Canada [20][21][22][23], MIDs have not yet been well established in this country. The objectives of this study were to measure the EQ-5D-derived health utilities associated with the selected chronic conditions and to estimate their MIDs based on the Commonwealth Fund Survey of Sicker Adults in Canada.…”

Blood levels of vitamin D and health‐functional status in asymptomatic individuals: a cross sectional study

“…Only a few studies have investigated associations between vitamin D levels and aspects of general, emotional and functional health, and parameters of quality of life. A recently published cross-sectional study of older adults in Canada reported an association between vitamin D levels and health-related quality of life measured by the five-level EQ-5D (EQ-5D-5 L) instrument [14]. Patients with heart failure, diabetes and vitamin D insufficiency show worse physical function and lower muscle strength compared with patients without diabetes and adequate vitamin D levels [15].…”

Dolor músculo esquelético y vitamina D

“…Chao y Cols encontraron que los pacientes con niveles más altos de VD tenían significativamente menos probabilidades de reportar problemas con la movilidad y las actividades, además los puntajes de varias dimensiones de la calidad de vida (CV) relacionada con la salud aumentaban con el incremento de los niveles de VD 38 . Bergman y Cols encontraron en un estudio observacional con 100 pacientes en cuidado paliativo por cáncer, que hubo una asociación significativa entre los niveles bajos de VD y el mayor uso de opioides para el control del dolor (coeficiente beta -0.67; p=0.02) 39 .…”