Vitamin D and atopic dermatitis

Abstract

Recent studies have demonstrated the association between allergic diseases and vitamin D deficiency. In addition to its classical role in calcium homeostasis, vitamin D has been known for its effect on immunomodulation. Because immunologic mechanisms play a role in the pathogenesis of atopic dermatitis (AD), vitamin D may influence the activity of AD. Epidemiological studies, clinical studies, and in vitro studies have suggested that vitamin D may improve the symptoms of AD. The purpose of this paper is to review the present literature that suggests a potentially significant role for vitamin D in AD. (Allergy Asthma Respir Dis 2013;1:197-202

Factors associated with Atopic Dermatitis in Korean Adults: Based on the Korea National Health and Nutrition Examination Survey 2008 2013

“…In particular, studies have been conducted of its primary role as an immunological factor of the skin barrier. The reason for the increase in the incidence of allergic diseases is supported by the hypothesis that people do not get enough sunshine and lack vitamin D, which can cause immune control disorders [4,5]. A correlated International Study of Asthma and Allergies in Children (ISAAC) study reported a low incidence of AD in areas of high latitudes and low temperatures, which lead to less vitamin D synthesis.…”