Abstract:Although transfusion of blood components is becoming increasingly safe, the risk of transmission of known and unknown pathogens persists. The application of vitamin B2 (riboflavin) and UV light to pathogen inactivation has several appealing factors. Riboflavin is a naturally occurring vitamin with a well-known and well-characterized safety profile. This photochemical-based method is effective against clinically relevant pathogens and inactivates leukocytes without significantly compromising the content and the… Show more
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