Vitamin B12 reference intervals on Beckman, Roche and Siemens analytical platforms
Nuthar Jassam,
Thomas Bancroft,
Ahai Luvai
et al.
Abstract:Background: Vitamin B12 status is assessed primarily by total serum B12 using competitive binding methods. The lack of availability of a standard material, and high-level reference measurement procedure affects the trueness of B12 results. This results in variation between methods. This study aimed to determine the reference intervals for vitamin B12 on three routine analytical platforms.
Method: A prospective reference population of healthy individuals was recruited according to the IFCC CRIDL criteria.… Show more
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