Vitamin B1 for type B metabolic acidosis: An underrecognized approach

Dejman, Adriana; Riveros, Jason

doi:10.4103/1319-2442.248314

Cited by 5 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…She did not show other features of wet or dry beriberi. Thiamine deficiency has been described in the literature as one of the rare causes of type B lactic acidosis 5 …”

Section: Resultsmentioning

confidence: 99%

“…Thiamine deficiency has been described in the literature as one of the rare causes of type B lactic acidosis. 5 Given the background of suspected widespread thiamine deficiency in the community, infants presenting with acute encephalitic syndrome not associated with a febrile episode and having normal cerebrospinal fluid studies are treated by the hospital with parenteral thiamine along with antivirals. Recently, patients with the encephalitic form of infantile beriberi have been seen with classical hyperechogenicity of the basal ganglia (Fig.…”

Section: Cardiac Form Of Infantile Beriberimentioning

confidence: 99%

See 1 more Smart Citation

The rediscovery of thiamine deficiency disorders at a secondary level mission hospital in Northeast India

Koshy¹,

Thankaraj²,

Ismavel³

et al. 2020

Annals of the New York Academy of Sciences

View full text Add to dashboard Cite

In this article, we report the different presentations of thiamine deficiency disorders seen at a remote rural mission hospital in Northeast India, including investigations, treatment, and recovery. Two case studies, one of an infant with cardiac beriberi and the other of a nonalcoholic adult presenting with peripheral neuropathy, cardiomyopathy, and metabolic acidosis and responding to thiamine supplementation, are described in detail. We share our experience with these clinical entities over the past two decades, including recent research and lessons learned, and suggest ways forward to identify at‐risk populations in Northeast India, improve early diagnosis and treatment, and promote preventive public health strategies.

show abstract

“…She did not show other features of wet or dry beriberi. Thiamine deficiency has been described in the literature as one of the rare causes of type B lactic acidosis 5 …”

Section: Resultsmentioning

confidence: 99%

Section: Cardiac Form Of Infantile Beriberimentioning

confidence: 99%

The rediscovery of thiamine deficiency disorders at a secondary level mission hospital in Northeast India

Koshy¹,

Thankaraj²,

Ismavel³

et al. 2020

Annals of the New York Academy of Sciences

View full text Add to dashboard Cite

show abstract

“…There are very few reported cases of MCL associated with type B lactic acidosis [ 14 , 33 – 36 ]. We have described a case of successfully treated type B lactic acidosis in a patient with MCL.…”

Section: Discussionmentioning

confidence: 99%

Type B Lactic Acidosis in a Patient with Mantle Cell Lymphoma

Nzenwa

Berquist

Brenner

et al. 2023

Case Reports in Critical Care

View full text Add to dashboard Cite

Type B lactic acidosis is an uncommon medical emergency in which acid production overwhelms hepatic clearance. This specific etiology of lactic acidosis occurs without organ hypoperfusion and has been most commonly described in patients with hematologic malignancies but also in patients with solid tumors. The mechanism by which cancer cells switch their glucose metabolism toward increasingly anaerobic glycolytic phenotypes has been described as the “Warburg effect.” Without treating the underlying malignancy, the prognosis for patients diagnosed with malignancy-related type B lactic acidosis is extremely poor. Here, we present a case of a 66-year-old male who was diagnosed with type B lactic acidosis secondary to mantle cell lymphoma. Bicarbonate drip was started to correct the lactic acidosis. The patient was also immediately treated with rituximab chemotherapy combined with rasburicase to avoid the hyperuricemia associated with tumor lysis syndrome. He responded to the early treatment and was discharged with normal renal function. Type B lactic acidosis secondary to hematologic malignancy is important to recognize. In order to successfully treat this syndrome, early diagnosis and simultaneous treatment of the imbalance of lactic acid levels and the underlying malignancy are necessary.

show abstract

“…This indicated that the patient's lactic acidosis might be due to some cause other than infection. Thiamine deficiency leads to increase in LA production, 3,4 this patient's anorexia lasting 6 months, haemodialysis increased the elimination of thiamine. After lactic acidosis, thiamine was administered, and the LA level remained normal thereafter.…”

mentioning

confidence: 81%

A case of severe lactic acidosis in a maintenance haemodialysis patient caused by thiamine deficiency: A case report

Yang

2021

Nephrology

View full text Add to dashboard Cite

Vitamin B1 for type B metabolic acidosis: An underrecognized approach

Cited by 5 publications

References 0 publications

The rediscovery of thiamine deficiency disorders at a secondary level mission hospital in Northeast India

The rediscovery of thiamine deficiency disorders at a secondary level mission hospital in Northeast India

Type B Lactic Acidosis in a Patient with Mantle Cell Lymphoma

A case of severe lactic acidosis in a maintenance haemodialysis patient caused by thiamine deficiency: A case report

Contact Info

Product

Resources

About