Vitamin B<sub>12</sub> Deficiency in Children

Jain, Rahul; Singh, Abhishek; Mittal, Medha; Talukdar, B

doi:10.1177/0883073813516194

Cited by 32 publications

(26 citation statements)

References 15 publications

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“…Equally common is weaning failure due to anorexia, refusal to solid foods, and spitting. [ 1 5 6 15 ] Even when weaning has been started, foods of animal origin including top milk are missing from the diet[ 5 18 ] or given in insufficient quantity. [ 12 14 19 ]…”

Section: Epidemiologymentioning

confidence: 99%

“…[ 1 8 9 10 11 13 ] Others have reported failure to thrive and wasted or marasmic look. [ 4 5 10 11 12 15 20 ] In any case, growth parameters are normal at birth and for the first 5–6 months of age. Later growth faltering occurs due to inadequate feeding caused by continued exclusive breastfeeding.…”

Section: Clinical Manifestationsmentioning

confidence: 99%

“…[ 22 ] Intercurrent illness may trigger rapid downhill course at any time during the course of illness. [ 1 4 5 8 22 ] Seizures are uncommon and may occur any time during the course of the disease. [ 5 13 22 ]…”

Section: Clinical Manifestationsmentioning

confidence: 99%

“…While dimorphic peripheral smear has been reported by many authors,[ 4 16 18 20 23 ] others have stressed the predominance of macrocytic morphology of the red blood cells. [ 1 5 6 11 22 ] Bone marrow findings have varied from predominantly normoblastic[ 10 11 13 ] through dimorphic[ 16 23 ] to predominantly megaloblastic. [ 1 3 8 9 20 ]…”

Section: Laboratory Investigationsmentioning

confidence: 99%

“…A number of important papers have been published since this last review. [ 3 4 5 6 ] The current review is being undertaken to provide up-to-date information on the infantile tremor syndrome (ITS) to the academic and practicing clinicians and also to critically analyze the issue of its etiology.…”

Section: Introductionmentioning

confidence: 99%

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Infantile tremor syndrome: A review and critical appraisal of its etiology

Goraya

Kaur

2016

J Pediatr Neurosci

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Infantile tremor syndrome (ITS) is defined by the tetrad of pallor, developmental delay/regression, skin pigmentation, and brown scanty scalp hair. Involuntary movements in the form of tremors supervene in the natural course of the illness in a significant number of cases. The disorder occurs in exclusively breast-fed infants of vegetarian mothers belonging to economically deprived sections of society. Most of the children eventually recover but are frequently left with long-term cognitive and language neurodeficits. ITS continues to be seen in clinical practice, but there has been no consensus on its causation. Last comprehensive review was published in 1987 describing the ITS as a syndrome of unknown or multiple etiologies. Several important papers have been published since then. This review attempts to provide comprehensive and up-to-date information on the subject incorporating recently published studies. In the end, the issue of etiology is objectively re-examined in the light of available evidence some of which has been published in recent years.

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