Vitamin a and Skin Disease

Leitner, Z. A.; Moore, Thomas

doi:10.1016/s0140-6736(46)90760-x

Cited by 32 publications

(8 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Low levels of serum vitamin A have also been noted in ichthyosis (Rapaport et al, 1942;Peck et al, 1943a;Leitner and Moore, 1946), pityriasis rubra pilaris (Leitner and Moore, 1946;Leitner and Ford, 1947)the similarity of the latter to the lesions found in vitamin-A deficiency has been stressed by Pettler (1936) and by Sutton and Sutton (1949)-and less frequently in commoner skin diseases such as eczema and psoriasis (Marchionini and Patel, 1937). Moore (1957) differentiates between skin lesions due to " dietary " and those due to " secondary " vitamin-A deficiency.…”

Section: Resultsmentioning

confidence: 97%

“…The association between various hyperkeratotic and dyskeratotic skin diseases and hypovitaminosis-A has been noted (Rapaport et al, 1942;Peck et al, 1943aPeck et al, , 1943bLeitner and Moore, 1946;Leitner and Ford, 1947). Low blood levels of vitamin A were found in tylosis (Porter, 1951) and some improvement in the skin lesions occurred on giving high doses of the vitamin.…”

Section: Discussionmentioning

confidence: 96%

See 1 more Smart Citation

Hypovitaminosis-A in a Family with Tylosis and Clinodactyly

Anderson¹

1961

BMJ

View full text Add to dashboard Cite

Section: Resultsmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 96%

Hypovitaminosis-A in a Family with Tylosis and Clinodactyly

Anderson¹

1961

BMJ

View full text Add to dashboard Cite

“…

…”

mentioning

confidence: 97%

Vitamin A and vitamin E in human blood

Leitner¹,

Moore

Sharman

1960

Br J Nutr

Self Cite

View full text Add to dashboard Cite

The work to be described in these communications followed earlier studies (Leitner & Moore, 1946;Leitner, Moore & Sharman, 1947), which were mainly concerned with the lowered blood vitamin A in certain diseases. For purposes of comparison it was desired to know the levels of vitamin A prevalent in normal subjects, and the advisability of obtaining more adequate information became apparent. It was known that the blood vitamin A varied widely in different normal individuals, and that men tended to have higher levels than women (Kimble, 1938-9), but knowledge was scanty on the influence of age or season of the year. Moreover, at the time of our earlier work, dietary restrictions, imposed during the Second World War, were still in force in this country. It was of interest, therefore, to study the effect on the blood vitamin A of the changes in the national food supplies which followed the gradual relaxation of controls.Specimens of blood were taken for a long period from numerous subjects, with the aim of collecting a mass of information large enough to counteract the disturbing effect on averages of the wide individual variations. Estimations of total carotenoids were made parallel with those of vitamin A. Vitamin E is known to be capable of intervening in the metabolism of vitamin A (Moore, 1939; Bacharach, 1940; Harris & Woodside, 194z), so our programme was extended to include estimations of vitamin E. The presentation of our results on vitamin E has, however, been assigned to a later communication (paper no. 2 of this series), and paper no. 3 will deal with observations on chronic hospital patients. E X P E R I M E N T A LCollection of specimens. Blood was collected by venepuncture from volunteers who came to one of us (2. A. L.) for medical examination. Some were young men in good health, who were examined for purposes of life insurance or for their fitness to do arduous work abroad. Most of the subjects, however, had some complaint, and were examined with a view to diagnosis and treatment.

show abstract

“…Darier's disease and pityriasis rubra pilaris, we found in some cases severe impairment of liver function particularly when we were using the hippuric-acid test (Leitner, 1947a;Leitner & Moore, 1946b, whereas Porter & Brunauer (1949), using mainly other liver function tests, could fmd only minor abnormalities. The urinary excretion of vitamin A in kidney and other diseases may be connected with the inability of the damaged liver to store the vitamin.…”

Section: Carotenoids Before Dosingmentioning

confidence: 79%

Pathology of Vitamin A Deficiency and its Clinical Significance

Leitner¹

1951

Br J Nutr

View full text Add to dashboard Cite

Vitamin a and Skin Disease

Cited by 32 publications

References 31 publications

Hypovitaminosis-A in a Family with Tylosis and Clinodactyly

Hypovitaminosis-A in a Family with Tylosis and Clinodactyly

Vitamin A and vitamin E in human blood

Pathology of Vitamin A Deficiency and its Clinical Significance

Contact Info

Product

Resources

About