Visuoperceptive Impairments in Severe Alcohol Use Disorder: A Critical Review of Behavioral Studies

Creupelandt, Coralie; Maurage, Pierre; D’Hondt, Fabien

doi:10.1007/s11065-020-09469-x

Cited by 9 publications

(7 citation statements)

References 241 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Reduced static amplitude of accommodation, slight mydriasis, peripheral parasympathetic neuropathy, isolated ametropia, cataract, or age-related macular degeneration are associated with alcohol consumption. More serious deficits have been noted in individuals with a long history of severe AUD [22]. This narrative review by Creupelandt et al highlighted a lower recovery rate in older participants with severe AUD, mainly among those with the longest severe AUD periods [22].…”

Section: Discussionmentioning

confidence: 98%

“…In a critical narrative review, Creupelandt et al [22] reviewed articles on visuoperceptive impairments in severe alcohol use disorder (AUD) in the last seven decades. The included studies investigated the long-term effects of chronic alcohol intake.…”

Section: Discussionmentioning

confidence: 99%

“…The authors highlighted the general paucity of research on the long-lasting visuoperceptive abilities among individuals with AUD. Additionally, the recruitment of heterogeneous groups with different comorbidities, various rates of lifetime alcohol consumption, and diverse abstinence periods made it challenging to draw comprehensive conclusions [22]. Both parvocellular and magnocellular damage have been reported in participants with AUD.…”

Section: Discussionmentioning

confidence: 99%

“…More serious deficits have been noted in individuals with a long history of severe AUD [22]. This narrative review by Creupelandt et al highlighted a lower recovery rate in older participants with severe AUD, mainly among those with the longest severe AUD periods [22]. The authors proposed interventions such as cognitive training programs in addition to visuoperceptive exercises to enhance the recovery of visuoperceptive deficits in severe AUD [22].…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Binocular vision parameters in chronic heavy alcoholics: Short-term outcomes of alcohol detoxification

Nagaraj¹,

Kamath²,

Goyal³

2022

Med Hypothesis Discov Innov Optom

View full text Add to dashboard Cite

Background: Alcohol consumption is rising in developing countries such as India, and alcohol addiction has systemic and ocular impacts. This study aimed to investigate the binocular functions of chronic heavy alcoholics before and after alcohol detoxification. Methods: A prospective before–after study was designed and conducted at Treda De-Addiction Centre, Bengaluru, India. Males in the age range of 30–40 years who had been alcohol addicts for more than six years and met the inclusion criteria were recruited. We performed a routine optometric examination followed by detailed binocular vision assessment, including accommodative, vergence, and oculomotor tests on the first day of rehabilitation and one month after initiation of rehabilitation. Results: Twenty-five males with of the age (mean ± standard deviation [SD]) 36.24 ± 4.33 years were evaluated. The pre- and post-detoxification mean ± SD of the monocular (right eye: 5.98 ± 3.50, 6.60 ± 3.49; left eye: 6.18 ± 3.69, 7.10 ± 3.78) and binocular accommodative facility (7.10 ± 3.93, 7.40 ± 4.51) did not change significantly (all P > 0.05). Eighteen (72%) of the participants had non-strabismic binocular vision anomalies (NSBVA), among whom the accommodative infacility and convergence insufficiency were higher in frequency and remained constant after alcohol detoxification. Furthermore, the binocular vision parameters showed no statistically significant difference between the pre- and post-detoxification values (all P > 0.05). Conclusions: The binocular vision parameters did not change significantly after one month of alcohol detoxification in the chronic heavy drinkers. Most long-term alcoholics had NSBVA with no change after rehabilitation, indicating that short-term alcohol detoxification may not aid in the recovery of binocular parameters. However, further validation is required. Assessing the impact of vision therapy in addition to a longer period of abstinence can confirm or refute the persistence of observed effects of chronic alcohol consumption on binocular functions and NSBVA in this population.

show abstract

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Binocular vision parameters in chronic heavy alcoholics: Short-term outcomes of alcohol detoxification

Nagaraj¹,

Kamath²,

Goyal³

2022

Med Hypothesis Discov Innov Optom

View full text Add to dashboard Cite

show abstract

“…The interest for visual processing in SAUD emerged from the observation that patients are often impaired in routinely used neuropsychological tasks requiring efficient visual analysis, such as the Rey-Oestherith Complex Figure copy or the WAIS Block Design and Object Assembly subtests (e.g., Beatty et al, 1997;Fitzhugh et al, 1960Fitzhugh et al, , 1965Jones, 1971;Wilson et al, 1988). Subsequent studies confirmed the presence of visual impairments by measuring visual evoked potentials, chromatic and achromatic vision, motion and speed processing, or peripheral visual field perception (Creupelandt and Maurage, 2021). They also showed that visual processing deficits may persist with long-term abstinence, inducing durable perceptual changes (da Cruz et al, 2016;Fein et al, 1990Fein et al, , 2006Yohman et al, 1985).…”

mentioning

confidence: 99%

Magnocellular and Parvocellular Mediated Luminance Contrast Discrimination in Severe Alcohol Use Disorder

Creupelandt

Maurage

Lenoble

et al. 2021

Alcoholism Clin & Exp Res

Self Cite

View full text Add to dashboard Cite

Background Severe alcohol use disorder (SAUD) is associated with widespread cognitive impairments, including low‐level visual processing deficits that persist after prolonged abstinence. However, the extent and characteristics of these visual deficits remain largely undetermined, impeding the identification of their underlying mechanisms and influence on higher‐order processing. In particular, little work has been conducted to assess the integrity of the magnocellular (MC) and parvocellular (PC) visual pathways, namely the 2 main visual streams that convey information from the retina up to striate, extrastriate, and dorsal/ventral cerebral regions. Methods We investigated achromatic luminance contrast processing mediated by inferred MC and PC pathways in 33 patients with SAUD and 32 matched healthy controls using 2 psychophysical pedestal contrast discrimination tasks that promote responses of inferred MC or PC pathways. We relied on a staircase procedure to assess participants’ ability to detect small changes in luminance within an array of 4 gray squares that were either continuously presented (steady pedestal, MC‐biased) or briefly flashed (pulsed pedestal, PC‐biased). Results We replicated the expected pattern of MC and PC contrast responses in healthy controls. We found preserved dissociation of MC and PC contrast signatures in SAUD but higher MC‐mediated mean contrast discrimination thresholds combined with a steeper PC‐mediated contrast discrimination slope compared with healthy controls. Conclusion These findings indicate altered MC‐mediated contrast sensitivity and PC‐mediated contrast gain, confirming the presence of early sensory disturbances in individuals with SAUD. Such low‐level deficits, while usually overlooked, might influence higher‐order abilities (e.g., memory, executive functions) in SAUD by disturbing the “coarse‐to‐fine” tuning of the visual system, which relies on the distinct functional properties of MC and PC pathways and ensures proper and efficient monitoring of the environment.

show abstract

Spatial frequency processing and its modulation by emotional content in severe alcohol use disorder

et al. 2022

View full text Add to dashboard Cite

Rationale Visuo-perceptive deficits in severe alcohol use disorder (SAUD) remain little understood, notably regarding the respective involvement of the two main human visual streams, i.e., magnocellular (MC) and parvocellular (PC) pathways, in these deficits. Besides, in healthy populations, low-level visual perception can adapt depending on the nature of visual cues, among which emotional features, but this MC and PC pathway adaptation to emotional content is unexplored in SAUD. Objectives To assess MC and PC functioning as well as their emotional modulations in SAUD. Methods We used sensitivity indices (d′) and repeated-measures analyses of variance to compare orientation judgments of Gabor patches sampled at various MC-and PC-related spatial frequencies in 35 individuals with SAUD and 38 matched healthy controls. We then explored how emotional content modulated performances by introducing neutral or fearful face cues immediately before the Gabor patches and added the type of cue in the analyses. Results SAUD patients showed a general reduction in sensitivity across all spatial frequencies, indicating impoverished processing of both coarse and fine-scale visual content. However, we observed selective impairments depending on facial cues: individuals with SAUD processed intermediate spatial frequencies less efficiently than healthy controls following neutral faces, whereas group differences emerged for the highest spatial frequencies following fearful faces. Altogether, SAUD was associated with mixed MC and PC deficits that may vary according to emotional content, in line with a flexible but suboptimal use of low-level visual content. Such subtle alterations could have implications for everyday life's complex visual judgments.

show abstract

Visuoperceptive Impairments in Severe Alcohol Use Disorder: A Critical Review of Behavioral Studies

Cited by 9 publications

References 241 publications

Binocular vision parameters in chronic heavy alcoholics: Short-term outcomes of alcohol detoxification

Binocular vision parameters in chronic heavy alcoholics: Short-term outcomes of alcohol detoxification

Magnocellular and Parvocellular Mediated Luminance Contrast Discrimination in Severe Alcohol Use Disorder

Spatial frequency processing and its modulation by emotional content in severe alcohol use disorder

Contact Info

Product

Resources

About