“…Amino acids, a feeding stimulant in fishes (Zielinski and Hara, 2006), are detected primarily by microvillous ORNs (Lipschitz and Michel, 2002;Sato and Suzuki, 2001), but also possibly by ciliated and crypt ORNs (Hansen et al, 2004;Vielma et al, 2008). In contrast, several studies demonstrated that for teleosts, bile salts are detected only by ciliated ORNs (Døving et al, 2011;Hansen et al, 2003;Sato and Suzuki, 2001). Additionally, cross-adaptation and mixture experiments confirm that teleosts possess ORs for bile salts that are independent from those for amino acids, prostaglandins, gonadal steroids and polyamines (Laberge and Hara, 2004;Michel and Derbidge, 1997;Zhang and Hara, 2009).…”