Visualized analysis of hotspots and frontiers in diabetes-associated periodontal disease research: a bibliometric study

Abstract

Background: Diabetes-associated periodontal disease is caused by diabetes-enhanced host immuneinflammatory responses to bacterial insult. An increasing number of papers related to diabetes-associated periodontal disease have been published. This study analyzed research on diabetes-associated periodontal disease with bibliometrics methods. The objective of this study was to identify hotspots and frontiers in the diabetes-associated periodontal disease research field.Methods: Publications were extracted from the Web of Science core collection database, and the document types included were limited to articles and reviews. The bibliometric analysis software CiteSpace5 was used to analyze the number of articles, research fields, countries/regions, institutions, authors, keywords, and other information. Outcomes were visualized to analyze the hotspots and research frontiers of diabetesassociated periodontal disease.Results: A total of 3,572 articles were retrieved. Among the research fields, dentistry, oral surgery, and medicine accounted for the highest proportion of publications, and public, environmental, and occupational health had the highest betweenness centrality. The number of publications from the United States ranked first among all the countries, while Columbia University ranked first among all the institutions. Global cooperation was not frequent. Keyword analysis showed that inflammatory pathways were the hotspots.Burst words analysis indicated that early prevention was a research frontier. Conclusions:The bibliometric method helped identify research hotspots and frontiers. Inflammatory pathways were hotspots, and early prevention was a frontier in diabetes-associated periodontal disease.

The Interplay Between Diabetes and Oral Health: A Comprehensive Bibliometric Analysis of Clinical Trials (1967-2024)

“…To the best of our knowledge, no bibliometric analysis on this topic has been done till now. However, few bibliometric studies that explored the literature regarding the relationship between diabetes focused on any one aspect related to oral health, such as periodontal diseases and oral implants [20][21][22][23]. Our bibliometric analysis sheds light on the robust research landscape concerning the impact of diabetes on oral health, indicating a growing recognition of the importance of this interplay.…”

Association between Chronic Gingivitis and Cancer: A Retrospective Cohort Study of 19,782 Outpatients from the United Kingdom

“…Periodontal disease, including the two medical conditions gingivitis and periodontitis, represents a major global health burden with a high prevalence, especially in older patients [ 1 ]. Both diseases are characterized by an ongoing inflammation within the oral cavity as well as systemic inflammation status, which can lead to “systemic sequela”, including cardiovascular diseases, diabetes, respiratory diseases, and chronic kidney disease [ 7 , 8 , 9 , 10 , 11 , 12 ]. Moreover, both experimental and epidemiologic studies previously suggested an increased incidence of cancer in patients with chronic gingivitis, but many questions, including the statistical strength of the associations and the specific profile of malignancies, have remained open.…”

“…Along with local complications, including bleeding and tooth loss, periodontal diseases have been linked to several systemic diseases and conditions, making them a significant risk factor [ 4 ], which is not sufficiently recognized by most patients [ 5 , 6 ]. Studies have shown that periodontal diseases can increase the risk of cardiovascular diseases, ankylosing spondylitis, diabetes, respiratory diseases, and chronic kidney disease [ 7 , 8 , 9 , 10 , 11 , 12 ]. The presence of periodontal disease has also been associated with adverse pregnancy outcomes, such as preterm birth and low birth weight [ 13 , 14 ].…”