Visual stimuli modulate frontal oscillatory rhythms in a cortically blind patient: Evidence for top-down visual processing

Tipura, Eda; Pegna, Alan J.; Gelder, Béatrice de; Renaud, Olivier

doi:10.1016/j.clinph.2017.02.009

Cited by 2 publications

(1 citation statement)

References 51 publications

(53 reference statements)

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“…This is exemplified by a task-based study that showed lower alpha activity in response to an increased state of alertness (Del Zotto et al, 2013), generally referred to as event-related desynchronization. Alpha phase synchronization and longdistance phase coherence have also been consistently linked to attentive and cognitive control as a top-down modulation (Fries, 2005;Klimesch et al, 2006;Thangavel et al, 2011;Tipura et al, 2017). Thus, via suppression of irrelevant information, this topdown modulated mechanism could increase the signal-to-noise ratio in attentive and cognitive processing (Jensen and Mazaheri, 2010;Klimesch, 2012).…”

Section: Discussionmentioning

confidence: 99%

Reduced Functional Connectivity in Children With Congenital Cataracts Using Resting-State Electroencephalography Measurement

et al. 2021

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ObjectivesNumerous task-based functional magnetic resonance imaging studies indicate the presence of compensatory functional improvement in patients with congenital cataracts. However, there is neuroimaging evidence that shows decreased sensory perception or cognition information processing related to visual dysfunction, which favors a general loss hypothesis. This study explored the functional connectivity between visual and other networks in children with congenital cataracts using resting state electroencephalography.MethodsTwenty-one children with congenital cataracts (age: 8.02 ± 2.03 years) and thirty-five sex- and age-matched normal sighted controls were enrolled to investigate functional connectivity between the visual cortex and the default mode network, the salience network, and the cerebellum network during resting state electroencephalography (eyes closed) recordings.ResultThe congenital cataract group was less active, than the control group, in the occipital, temporal, frontal and limbic lobes in the theta, alpha, beta1 and beta2 frequency bands. Additionally, there was reduced alpha-band connectivity between the visual and somatosensory cortices and between regions of the frontal and parietal cortices associated with cognitive and attentive control.ConclusionThe results indicate abnormalities in sensory, cognition, motion and execution functional connectivity across the developing brains of children with congenital cataracts when compared with normal controls. Reduced frontal alpha activity and alpha-band connectivity between the visual cortex and salience network might reflect attenuated inhibitory information flow, leading to higher attentional states, which could contribute to adaptation of environmental change in this group of patients.

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