Visual Prognoses Correlated with the Presence of Interna-limiting Membrane in Histopathologic Specimens Obtained from Epiretinal Membrane Surgery

Sivalingam, Arunan; Eagle, Ralph C.; Duker, Jay S.; Brown, Gary C.; Benson, William E.; Annesley, William H.; Federman, Jay L.

doi:10.1016/s0161-6420(90)32378-3

Cited by 94 publications

(51 citation statements)

References 13 publications

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“…It has been suggested that removal of the ILM may be associated with a decreased chance of visual improvement [18]. Others have supported that the removal of the ILM does not have any adverse effects on vision [19]. In our report, the removal of the epimacular tissue results in marked improvement of vision and reduction of metamorphopsia in most patients.…”

Section: Discussionsupporting

confidence: 67%

Surgical Management of Epiretinal Membrane with Indocyanine-Green-Assisted Peeling

Sorcinelli

2003

Ophthalmologica

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Purpose: To evaluate the surgical results of pars plana vitrectomy with peeling of the inner limiting membrane (ILM) in a preliminary series of 28 eyes with macular epiretinal membrane (ERM). Methods: Pars plana vitrectomy with peeling of the ERM was performed on 28 eyes. All preretinal macular tissues were removed including the ILM after injection of indocyanine green (ICG) solution. Results: Postoperatively visual acuity improved within 3 months by at least 2 lines in 26 eyes. Neither the deterioration of the macula nor the recurrence of the ERM was observed during the entire period of review (6 months; range 4–8 months). Conclusions: Vitrectomy including ICG-assisted peeling of the ERM leads to an expedited resolution of the macular pucker and improvement of visual acuity, without subsequent formation of ERMs.

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Section: Discussionsupporting

confidence: 67%

Surgical Management of Epiretinal Membrane with Indocyanine-Green-Assisted Peeling

Sorcinelli

2003

Ophthalmologica

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“…The first study of macular ERM removal with ILM peeling reported a less favorable visual outcome [15] . However, it remains controversial whether ILM peeling during ERM surgery is beneficial for postoperative visual function and retinal morphology.…”

Section: Discussionmentioning

confidence: 99%

Changes in Retinal Thickness after Vitrectomy for Epiretinal Membrane with and without Internal Limiting Membrane Peeling

et al. 2016

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Purpose: To investigate anatomic changes in retinal thickness (RT) and functional changes after vitrectomy for idiopathic epiretinal membranes (ERMs) with and without internal limiting membrane (ILM) peeling. Methods: The medical records of 100 eyes of 96 patients with ERM who underwent vitrectomy and ERM removal were reviewed retrospectively. The RT was measured by optical coherence tomography, and the area was divided into 9 sections. The best-corrected visual acuity (BCVA), 9 RT areas, and incidence rates of recurrent ERM were compared between the groups with and without ILM peeling before the operation and 12 months postoperatively. Results: Thirty-nine eyes that underwent vitrectomy with ILM peeling and 61 eyes that underwent vitrectomy without ILM peeling met the inclusion criteria. There were no significant differences between the groups in the BCVA and any of the RTs before the operation and 12 months postoperatively. The ERMs recurred in 8 (20.5%) of 39 eyes and 26 (42.6%) of 61 eyes in the groups with and without ILM peeling, respectively, with a difference that reached significance (p = 0.02) 12 months postoperatively. Conclusions: Vitrectomy for ERM affects the BCVA or the RTs 12 months postoperatively. Additional ILM peeling does not affect them, but it might reduce the ERM recurrence rate.

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“…Until the introduction of ICG for ILM peeling and the reports on potential ICG-related toxic effects, only single reports related ILM peeling to impaired functional outcome [52] . However, subtle functional and morphological alterations were infrequently observed following macular surgery with ILM peeling, including changes of the focal macular electroretinogram (ERG) [53] , dissociated optic nerve fiber layer (DONFL) appearance [54][55][56] , paracentral scotomata or visual field defects [57,58] .…”

Section: Retinal Function and Chromovitrectomymentioning

confidence: 99%

Chromovitrectomy and the Vitreoretinal Interface

Schumann¹,

Haritoglou²

2013

Ophthalmologica

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It still remains unclear to which extent the presence and the amount of retinal debris seen in internal limiting membrane (ILM) specimens harvested during macular surgery for macular holes or epiretinal membranes are related to the procedure of ILM peeling itself or to modifications of the surgical technique, such as application of vital dyes for visualization of the ILM, or to pathological conditions with epiretinal membrane formation at the vitreoretinal interface. The presence of cellular fragments on the retinal side of the removed ILM appears to be of multifactorial origin, and additional causes besides dye application need to be considered. However, morphological studies with evaluation of vital dyes are still of relevance and provide additional insights into the ultrastructure of the vitreoretinal interface and its interaction with adjuvants used during macular surgery. Chromovitrectomy is an emerging field in vitreoretinal surgery. It is of importance to better understand the tissue-dye interactions, which not only alter the mechanical properties of the tissue being stained, but may also have an impact on the functional result postoperatively.

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Visual Prognoses Correlated with the Presence of Interna-limiting Membrane in Histopathologic Specimens Obtained from Epiretinal Membrane Surgery

Cited by 94 publications

References 13 publications

Surgical Management of Epiretinal Membrane with Indocyanine-Green-Assisted Peeling

Surgical Management of Epiretinal Membrane with Indocyanine-Green-Assisted Peeling

Changes in Retinal Thickness after Vitrectomy for Epiretinal Membrane with and without Internal Limiting Membrane Peeling

Chromovitrectomy and the Vitreoretinal Interface

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