Visual Outcomes After Epi-LASIK and PRK for Low and Moderate Myopia

Sia, Rose K.; Coe, C. D.; Edwards, J. D.; Ryan, Denise S.; Bower, Kraig S.

doi:10.3928/1081597x-20111004-01

Cited by 16 publications

(10 citation statements)

References 19 publications

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“…16,17 However, no such advantages have been confirmed and, in fact, some have reported increased pain, delayed epithelial healing, and inferior early visual outcomes compared with flap-off techniques. [18][19][20] The flap-off variant of this technique was termed Epi-LASIK flap-off (Epi-LASIK FO). 8,18 The advantage of Epi-LASIK and Epi-LASIK FO is absence of alcohol-related toxicity and possibly faster time to healing.…”

Section: Resultsmentioning

confidence: 99%

Long-Term Visual and Refractive Outcomes following Surface Ablation Techniques in a Large Population for Myopia Correction

Kulkarni

AlMahmoud

Priest

et al. 2013

Invest. Ophthalmol. Vis. Sci.

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Section: Resultsmentioning

confidence: 99%

Long-Term Visual and Refractive Outcomes following Surface Ablation Techniques in a Large Population for Myopia Correction

Kulkarni

AlMahmoud

Priest

et al. 2013

Invest. Ophthalmol. Vis. Sci.

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“…Specially designed micro‐keratomes for epithelial removal (epi‐LASIK) have been developed; however, published results are again conflicting. A recent non‐randomised study by Sia and colleagues comparing outcomes after epi‐LASIK and PRK, showed superior refractive efficacy and stability with epi‐LASIK but slower re‐epithelialisation. A RCT by Teus, de Benito‐Llopis and García‐González comparing LASEK and epi‐LASEK demonstrated faster visual rehabilitation and better safety and efficacy after LASEK for low to moderate myopic corrections, while Hondur, Bilgihan and Hasanreisoglu in a prospective, bilateral study of epi‐LASIK and LASEK for myopia found comparable results between the two methods at one year and in a retrospective chart review, Reilly and colleagues found less pain and a trend toward less haze with epi‐LASIK.…”

Section: Comparison Of Methods For Epithelial Removalmentioning

confidence: 99%

“…The results of these studies, while conflicting, all report excellent visual and refractive outcomes with surface ablation techniques. Generally, there appear to be little differences in final refractive and visual outcomes between all the different epithelial removal techniques . Further randomised clinical trials are necessary but at present there appears to be little to choose between the various methods and the technique for epithelial removal can be left to the preference of the individual surgeon.…”

Section: Comparison Of Methods For Epithelial Removalmentioning

confidence: 99%

“…Generally, there appear to be little differences in final refractive and visual outcomes between all the different epithelial removal techniques. [32][33][34][35][36][37][38][39][40][41][42] Further randomised clinical trials are necessary but at present there appears to be little to choose between the various methods and the technique for epithelial removal can be left to the preference of the individual surgeon.…”

Section: Comparison Of Methods For Epithelial Removalmentioning

confidence: 99%

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Excimer laser surface ablation: a review of recent literature

O’Brart

2014

Clinical and Experimental Optometry

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The aim was to review the recently published literature on excimer laser surface ablation procedures, including photorefractive keratectomy (PRK), laser sub-epithelial keratomileusis (LASEK), microkeratome-assisted PRK (epi-LASIK) and trans-epithelial (laser-assisted) PRK, to help elucidate where and how surface ablation may best fit into current refractive surgical practice. The emphasis was on publications within the last three years and included systemic reviews, meta-analyses and randomised controlled trials. Where such evidence did not exist, selective large series cohort studies, case-controlled studies and case series with follow-up preferably greater than six months were examined and included. Refractive and visual outcomes are excellent and comparable to those after LASIK even in complex cases after previous corneal surgery. Indeed, surface ablation combined with corneal collagen cross-linking may be used in selected eyes with biomechanical instability, where LASIK is contraindicated. In addition, there is evidence to suggest that there may be less induction of higher order aberrations with surface techniques. Long-term stability and safety appear to be extremely satisfactory. The literature supports the use of modern excimer laser surface treatments, with outcomes comparable to those after LASIK and evidence of less induction of higher-order aberrations. Follow-up studies at 10 to 20 years indicate excellent stability and safety.

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“…The patients were fitted with a -0.50 D bandage contact lens with base curve of 8.6, until the epithelium healed (3-7 days). 17,18,19 Postoperatively, a nonsteroidal anti-inflammatory drop, ketorolac 0.5% was used at the time of surgery and continued four times a day for the first 24 hours. A solution of dilute tetracaine in artificial tears was given for use on an as needed basis to mitigate ocular discomfort.…”

Section: Surgical Techniquesmentioning

confidence: 99%

Clinical Study to Evaluate the Visual Outcome and Patient Comfort in Lasik and Photorefractive Keratectomy in Low-to-Moderate Myopic Astigmatism Patients

P¹,

M²,

R³

et al. 2017

jebmh

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BACKGROUND To evaluate visual outcomes following LASIK and Photorefractive Keratectomy (PRK) in low-to-moderate myopia and/or myopic astigmatism in age and refractive error matched eyes. MATERIALS AND METHODS Of a total 30 patients aged ≥21 years, 20 (40 eyes) underwent LASIK and 10 (20 eyes) underwent PRK for low-to-moderate myopia or myopic astigmatism. LASIK was performed with the Alcon wave light 500 and PRK with the alcohol application for epithelial removal. All ablations were performed using the same excimer laser system. One surgeon operated all patients by using an excimer laser (Alcon wave light 500 system). Age and refractive error matched patients were divided in two groups. Preoperative and one year postoperative uncorrected visual acuity, best corrected visual acuity and manifest refractions were recorded to compare the outcomes of both the procedures. Outcome measures to assess the patient comfort levels in both groups include postoperative pain and quality of vision. Other outcome measures to assess the wound healing includes intraoperative complications, corneal haze and corneal reepithelialisation. RESULTS Sixty eyes of 30 patients were found matched regarding age and refractive error. In PRK group, among 10 patients, 5 (50%) were males and 5 (50%) were females, whereas in Lasik group, males were 12 (60%) and 8 (40%) were female patients. Mean preoperative MRSE was-4.06 ± 1.00 Dioptres (D) for LASIK versus-4.50 ± 1.25 D for PRK. Complete flap healing was achieved by postoperative day 4 in 86.9% of LASIK eyes versus complete reepithelialisation in 92.4% of PRK eyes. Using Fisher exact test, a significantly higher percentage of LASIK eyes compared to PRK eyes achieved 20/15 or better at 1 month (35.8% vs. 17.8%, P=0.031), 3 months (69.3% vs. 49.3%, P=0.004), 6 months (79.1% vs. 59.9%, P<0.001) and 12 months (85.9% vs. 61.9%, P=0.002). A change in MRSE >0.50 D occurred in 12.4% of LASIK eyes within the 3-and 12-month interval versus 25.7% of PRK eyes (P=0.04). Patients in both groups were happy regarding their visual outcome. CONCLUSION LASIK showed superior refractive efficacy and stability for low-to-moderate myopia with RBT (residual bed thickness) >320 microns. PRK shows better results in thinner corneas (RBT 280-320 microns). Both treatments were safe and comparable except in terms of pain and haze formation in selective PRK cases.

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Visual Outcomes After Epi-LASIK and PRK for Low and Moderate Myopia

Cited by 16 publications

References 19 publications

Long-Term Visual and Refractive Outcomes following Surface Ablation Techniques in a Large Population for Myopia Correction

Long-Term Visual and Refractive Outcomes following Surface Ablation Techniques in a Large Population for Myopia Correction

Excimer laser surface ablation: a review of recent literature

Clinical Study to Evaluate the Visual Outcome and Patient Comfort in Lasik and Photorefractive Keratectomy in Low-to-Moderate Myopic Astigmatism Patients

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