Visual outcome in cats with hypertensive chorioretinopathy

Young, W. E.; Zheng, Chaowen; Davidson, Michael G.; Westermeyer, Hans D.

doi:10.1111/vop.12575

Cited by 19 publications

(20 citation statements)

References 28 publications

(47 reference statements)

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“…The aim of this prospective study was to classify and evaluate the prevalence and outcome of ocular fundus abnormalities in a population of hypertensive cats. The prevalence of ocular lesions in cats affected by SHP is difficult to establish because the most recent studies are all retrospective 1,19,22,24 . In the literature, only one prospective study reports a 16% prevalence of ocular lesions in the examined population 8 .…”

Section: Discussionmentioning

confidence: 99%

“…Systemic hypertension (SHP) is defined as persistently high arterial blood pressure, and it is a recognized source of morbidity in both human and veterinary patients with specific systemic diseases 1–12 . Devastating damage caused by SHP is typically found in the eye, as well as the kidney, the heart, and the brain 4,7,8,10,12–24 , 27‐36 . Injury related to SHP in these organ systems is referred to as target organ damage (TOD) and is generally considered an indication for treatment with systemic antihypertensive drugs.…”

Section: Introductionmentioning

confidence: 99%

“…In the feline eye, SHP can lead to sudden blindness caused by progressive microvascular choroidopathy and retinopathy up to the onset of optic neuropathy 8,16,19,22,24,26 . Hypertensive cats with ocular disease commonly present with subretinal or intraretinal hemorrhages, and partial or complete bullous retinal detachment 8,18–20,22,24,26 . Anterior segment abnormalities reported with SHP include hyphema and anterior uveitis.…”

Section: Introductionmentioning

confidence: 99%

“…Hyphema may originate not only from anterior displacement of vitreal hemorrhages but also by iridal vessel damage from SHP 1,19 . Vitreous hemorrhages, in association with hyalitis, may also be present 22,24 . Ocular lesions secondary to SHP are usually diagnosed when a cat shows acute vision loss due to a complete retinal detachment.…”

Section: Introductionmentioning

confidence: 99%

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Ocular fundus abnormalities in cats affected by systemic hypertension: Prevalence, characterization, and outcome of treatment

Cirla

Drigo

Andreani³

et al. 2021

Veterinary Ophthalmology

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Objectives To determine the prevalence of ocular fundus abnormalities in cats with a diagnosis of systemic hypertension, to characterize the abnormalities observed, and to evaluate ophthalmoscopic evolution during treatment with amlodipine besylate. Animals studied Cats diagnosed as affected by SHP in a 2‐year period. Procedures Systemic hypertension was assessed by oscillometric blood pressure measurement, and its etiology was also established. All the cats received an ophthalmic examination, and ocular lesions were classified with a score from 0 (no abnormalities) to 4 (severe abnormalities). All cats received amlodipine besylate by mouth, and those that showed fundus abnormalities were regularly rechecked from 7 to 365 days after diagnosis. Data were statistically analyzed to compare Psys and Pdia with all the variables and to correlate Psys and Pdia with the fundus score. Results A total of 225 cats were enrolled in the study, and the prevalence of fundus abnormalities was 58.6% (21.2%: grade 1; 18.2%: grade 2; 36.4%: grade 3; and 24.2%: grade 4). Systemic hypertension was diagnosed concurrently with chronic renal failure (60.4%), hyperthyroidism (28.9%), both chronic renal failure and hyperthyroidism (7.6%), and hypertrophic myocardiopathy (3.1%). A significant effect of Psys values on the fundus score was detected. Amlodipine therapy improved fundus abnormalities in 50% of cases at the 21‐day follow‐up. Conclusions This study showed that fundus abnormalities are common in hypertensive cats at the time of the systemic diagnosis, and most of the abnormalities are moderate to severe. Treatment with amlodipine appeared to improve ophthalmic lesions over time.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Ocular fundus abnormalities in cats affected by systemic hypertension: Prevalence, characterization, and outcome of treatment

Cirla

Drigo

Andreani³

et al. 2021

Veterinary Ophthalmology

View full text Add to dashboard Cite

show abstract

“…In Studien konnten bereits Schädigungen der Retina ab einem systolischen Blutdruck von 160 mmHg nachgewiesen werden [1]. Häufig werden die Patienten aufgrund von Blindheit und beidseitiger Mydriasis infolge einer vollständigen Retinaablation und/oder einer intraokularen Blutung vorgestellt [1,6]. In einer Studie aus 2018 konnte gezeigt werden, dass bei bis zu 74 % der Katzen mit einer Retinaablösung unter Therapie eine Verbesserung des Visus eintritt [6].…”

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