2004
DOI: 10.1086/382884
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Visual Loss with West Nile Virus Infection: A Wider Spectrum of a “New” Disease

Abstract: We describe a case of severe visual loss as a result of West Nile virus (WNV) infection. Associated headache and fever led to the proper diagnosis and management, but the findings of optic neuritis, retinitis, and uveitis were a surprising and prominent component of the patient's meningitis syndrome. Physicians diagnosing and treating patients with WNV infection should be alerted to the possibility of ocular and optic nerve involvement, which may leave permanent neuropathic residua.

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Cited by 32 publications
(24 citation statements)
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“…viruses, such as chikungunya (19)(20)(21), dengue virus (DENV) (22)(23)(24), and West Nile virus (WNV) (25,26), in adults, including optic neuritis, retinal hemorrhages, and retinal edema. Therefore, it is highly unlikely that the microcephaly itself causes retinal abnormalities.…”
Section: Introductionmentioning
confidence: 99%
“…viruses, such as chikungunya (19)(20)(21), dengue virus (DENV) (22)(23)(24), and West Nile virus (WNV) (25,26), in adults, including optic neuritis, retinal hemorrhages, and retinal edema. Therefore, it is highly unlikely that the microcephaly itself causes retinal abnormalities.…”
Section: Introductionmentioning
confidence: 99%
“…Indocyanine green angiography shows well-delineated hypofluorescent choroidal lesions, which are more numerous than those appreciated by fluorescein angiography or clinically (Fig. 3C) [43].…”
Section: Chorioretinitismentioning
confidence: 89%
“…Since the first descriptions of ocular involvement secondary to WNV infection in 2002 and 2003, several ophthalmologic findings have been recognized, including chorioretinitis, anterior uveitis, retinal vasculitis, optic neuritis, and congenital chorioretinal scarring [26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44].…”
Section: Ocular Diseasementioning
confidence: 99%
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“…The symptoms include high-grade fever, myalgia, arthralgia, malaise, nausea, headache, skin rash, weakness, and pharyngitis [ 13 ]. The acute illness typically lasts less than a week.…”
Section: Clinical Symptoms and Signsmentioning
confidence: 99%