Visual loss due to paranasal sinus invasive aspergillosis in a diabetic patient

Abstract

Aspergillus species are commonly found in the soil and decaying organic matter. The spores can be typically inhaled or ingested, yet disease due to tissue invasion is rarely seen in the immunocompetent host. In the immunocompromised patient, there has been an increased incidence of invasive aspergillosis in the last 20 years. Invasive aspergillosis of the maxillary sinus with orbital and cranial spread can be lethal, therefore, necessitates early diagnosis and prompt treatment. The predilection of Aspergillus for infiltration of blood vessels can result in serious ocular complications which can lead to loss of vision. We present the case of an uncontrolled diabetic patient with invasive maxillary sinus aspergillosis and extension to the orbital contents. Our purpose was to emphasize the need of early recognition and prompt initiation of combined antifungal treatment and surgical intervention with the intent to preserve the involved vital structures.

Aspergillus terreus Meningitis in Immunocompetent Patient: A Case Report

“…Cryptococcus neoformans infection is still the most common CNS fungal infection, whereas Aspergillus and Mucor are relatively uncommon causes of CNS infection (Qi, 2014 ). Aspergillosis CNS fungal infection may present with various features depending on the pathogenicity of a specific pathogenic species and the status of the host's immune response (Rallis et al, 2014 ). The most common primary sites of aspergillosis are lungs, paranasal sinuses, and ear canal (Baddley et al, 2003 ).…”