Visual Field Damage in Myopic Glaucoma

Araie, Makoto

doi:10.1007/978-4-431-55672-5_5

Cited by 1 publication

(1 citation statement)

References 42 publications

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“…11 In addition to showing visual field (VF) deterioration, glaucoma with myopia has been also reported to be associated with a higher risk of cecocentral VF loss in early stages. 12,13 VF defects in the central VF directly affect the quality of vision, and thus can be a driving force alongside the VF deterioration rate for the initiation of early surgical treatments, such as trabeculectomy with mitomycin C (Trab MMC), in treating glaucoma with myopia.…”

Section: Introductionmentioning

confidence: 99%

Influence of Trabeculectomy with Mitomycin C on Longitudinal Changes in the Visual Field in Glaucoma Patients with High Myopia

Yamagata,

Suda,

Akagi

et al. 2023

OPTH

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Purpose To evaluate the effect of trabeculectomy (Trab MMC) on visual field (VF) progression in eyes with glaucoma and high myopia. Patients and Methods Patients diagnosed with primary open-angle glaucoma or exfoliation glaucoma who underwent Trab MMC as the first glaucoma surgery along with ≥3 VF tests preoperatively and postoperatively were enrolled. High myopia was defined as an axial length ≥26.5 mm. Postoperative reductions in intraocular pressure (IOP) were assessed by survival analysis using IOP measurements obtained preoperatively. The longitudinal trends of the outcome measures were evaluated using linear mixed models. Results Thirty-five eyes of 32 patients were included in this study, including 22 eyes of 20 patients in non-highly myopic group and 13 eyes of 12 patients in highly myopic group. IOP decreased after Trab MMC, and the survival rate did not differ significantly in relation to axial length. Linear mixed-model analyses suggested that the inhibitory effects of Trab MMC on the rate of mean deviation (MD) changes were significant in the non-highly myopic group (−0.53 ± 0.15 dB/year preoperatively to −0.16 ± 0.13 dB/year postoperatively; P = 0.004), but not in the highly myopic group (−0.66 ± 0.19 dB/year preoperatively to −0.48 ± 0.18 dB/year postoperatively; P = 0.32). Conclusion Trab MMC reduced IOP in both highly myopic and non-highly myopic eyes, and IOP reduction was very similar in both groups. The VF deterioration rate decreased in both groups, but the change was weaker and nonsignificant in the highly myopic group.

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Section: Introductionmentioning

confidence: 99%