“…The differentiation between ON and AION is not always straightforward since the two diseases share many signs and symptoms. Although a central scotoma has been regarded as the characteristic field defect of ON [2,4,5,9,11,12,13] and a sector scotoma as typical for AION [3,8,12,15], Rizzo and Lessell [16] found a considerable overlap of the visual field defects in ON and AION. Moreover, Keltner et al [10] concluded on the basis of 448 patients in the Optic Neuritis Treatment Trial: ªSince a wide variety of visual field defects can occur with an acute attack of optic neuritis, the pattern of visual field loss is of limited utility in distinguishing optic neuritis from ischemic optic neuropathy and other optic nerve disordersº.…”