Visual evoked-response attenuation by spreading depression.

Patterns of disruption of a lateralized discrimination by unilateral cortical spreading depression

“…However, examination of the EEG records obtained in the present experiment failed to reveal any simple consistent relation between the state of the EEG and the occurrence of either kind of error, possibly because only unilateral depression was elicited. Freedman and Langford ·(1969) have also shown that unilateral cortical spreading depression attenuates visual evoked responses not only in the depressed hemisphere but also on the untreated one, though not as much. The untreated hemisphere cannot therefore be considered to function normally.…”

“…Spreading depression is known to abolish or attenuate primary sensory cortical evoked potentials (BureS, 1959 ;BureS et al, 1974;Freedman & Langford, 1969). Other evidence suggests that sensory function is disrupted by this manipulation.…”