“…A better approach is to titrate the intake of DHA against the functional outcome of interest in intervention studies. The effect on visual and intellectual development of supplementation of formula milk with LCPUFA has been extensively studied (Lucas et al, 1992(Lucas et al, , 1998Birch et al, 1998;Horwood et al, 2001;Willatts, 2002;Auestad et al, 2003;O'Connor et al, 2003) and, on balance, the evidence suggests that an intake of preformed n-3 LCPUFA may be beneficial. Unfortunately, there are very few studies that deal specifically with supplementation during pregnancy.…”