Visual and spatial symptoms in Parkinson’s disease

Davidsdottir, Sigurros; Cronin‐Golomb, Alice; Lee, Alison

doi:10.1016/j.visres.2004.11.006

Cited by 233 publications

(213 citation statements)

References 84 publications

Supporting

Mentioning

200

Contrasting

Unclassified

Order By: Relevance

“…Barnes et al [5] did not observe greater deficits in hallucinating PD patients on the spatial perception subtest of the Visual Object and Space Perception Battery than in nonhallucinating PD patients. However, other authors found an association between hallucinatory experiences and difficulty estimating spatial relations [27] and visuospatial learning [4] . The continuous deterioration on the Visual Form Discrimination Test in our hallucinating PD patients would suggest a visuospatial progressive decline in addition to a visuoperceptive dysfunction.…”

Section: Discussionmentioning

confidence: 85%

Cognitive Changes in Parkinson’s Disease Patients with Visual Hallucinations

Ramı́rez-Ruiz¹,

Junqué²,

Martí³

et al. 2007

Dement Geriatr Cogn Disord

View full text Add to dashboard Cite

Objective: To evaluate the decline in specific neuropsychological functions in nondemented Parkinson’s disease (PD) patients with a history of visual hallucinations (VH). Methods: Twenty PD patients with VH, 20 PD patients without VH and 18 normal controls were followed up over a 1-year period and assessed for cognitive decline. Results: Forty-five percent of nondemented hallucinating PD patients developed dementia during the 1-year period between baseline and follow-up evaluations. Of the nondemented hallucinating PD patients nearly 70% showed impairment in multiple cognitive domains. The progressive decline in hallucinating PD patients affected mainly visual memory for faces and visuoperceptive-visuospatial functions. Conclusion: Our results support a fast impairment of complex visual functions in hallucinating PD patients, but also a progressive decline in multiple cognitive domains, which have been identified as a risk of developing dementia in PD.

show abstract

Section: Discussionmentioning

confidence: 85%

Cognitive Changes in Parkinson’s Disease Patients with Visual Hallucinations

Ramı́rez-Ruiz¹,

Junqué²,

Martí³

et al. 2007

Dement Geriatr Cogn Disord

View full text Add to dashboard Cite

show abstract

“…Hence, the basal ganglia may have a role during the co-regulation of force and timing of movement, especially when movement changes are required. It appears that freezing exemplifies a disruption of the co-regulation of timing and amplitude [15,32], no doubt brought on and magnified by multiple factors such as motor and postural adaptations [1] and visual/spatial deficits interacting with perception of the environment [35]. In addition, mental aspects [36] of emotional as well as cognitive origin and of which attention is possibly the most crucial factor [32,37], are considered contributory to lowering the threshold for the occurrence of freezing.…”

Section: Discussionmentioning

confidence: 99%

Does freezing in Parkinson’s disease change limb coordination?

et al. 2007

View full text Add to dashboard Cite

The aim of this study was to analyse the kinematic characteristics of the strides before freezing and compare this with a voluntary stop and ongoing gait. Also, we investigated whether gait profiles were different as a function of the side of the body. Ten patients were included with a mean age of 64.8 years (SD 5.1). Within a Vicon 3D gait laboratory, patients performed several trials of normal walking and voluntary stops or were exposed to circumstances, which provoked freezing in the off-phase of the medication cycle. Spatiotemporal and key kinematic data of the four strides prior to freezing were compared between body sides and walking conditions using multiple regression models for repeated measures. Prior to freezing patients had severely decreased movement ranges in the sagittal plane (ranging between 31% and 61.5%), most notably in the ankle and hip joints. The general shape of movement remained in the pre-freezing profiles with largely intact dissociation of knee and hip movement in stance but reduced dissociation in swing. Also present were reduced push-off movements in the ankle with fixed dorsiflexion, increased flexion in hip and knee and anterior tilt of the pelvis. During both voluntary (stopping) and involuntary deceleration (freezing), the body side with the last complete stride before the freeze, showed significantly smaller joint ranges (p < .01). Body side differences were larger than sequential deterioration of consecutive steps within each side. Freezing is distinct from normal deceleration of gait in that the reduction of propulsive movement is much greater. Despite hastening of steps, timing deficits did not affect overall movement shapes, except for the tendency to have a flexed walking pattern. The side of the body where gait terminated before freezing was in most cases the side of symptom-dominance, but not consistently so.

show abstract

“…Visual, 47,48 emotional, and cognitive triggers 49,50 of which distraction is possibly the most crucial one, 49 contribute to lowering the threshold for the occurrence of FOG. It appears that FOG-episodes frequently come to the fore in situations when reliance on basal ganglia control is periodically increased and attention is allocated elsewhere.…”

Section: Attention and Fogmentioning

confidence: 99%

Cueing for freezing of gait in patients with Parkinson's disease: A rehabilitation perspective

2008

View full text Add to dashboard Cite

Freezing of gait (FOG) has been known to respond favorably to sensory tricks and cues. However, FOG is a complex phenomenon with various motor control deficits at play. In this review, we examined and summarized the currently available evidence for the effectiveness of cueing for FOG to determine its value as a clinical method. The results showed that the immediate effects of cues have no consistent impact but longer periods of cued training may be beneficial. The review also showed (1) the limited statistical power and methodological weakness of the studies involved; (2) measurement difficulties of FOG, and (3) the need to better understand its underlying causal factors. Overall, the findings suggest a smaller capacity for compensation in patients suffering from FOG. Especially when attention is overloaded, the therapeutic window and the practical applicability of cueing seem more limited. These aspects need to be incorporated in the development of future cueing programs designed to alleviate FOG.

show abstract

Visual and spatial symptoms in Parkinson’s disease

Cited by 233 publications

References 84 publications

Cognitive Changes in Parkinson’s Disease Patients with Visual Hallucinations

Cognitive Changes in Parkinson’s Disease Patients with Visual Hallucinations

Does freezing in Parkinson’s disease change limb coordination?

Cueing for freezing of gait in patients with Parkinson's disease: A rehabilitation perspective

Contact Info

Product

Resources

About